CAPP_YERE8
ID CAPP_YERE8 Reviewed; 879 AA.
AC A1JI20;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Phosphoenolpyruvate carboxylase {ECO:0000255|HAMAP-Rule:MF_00595};
DE Short=PEPC {ECO:0000255|HAMAP-Rule:MF_00595};
DE Short=PEPCase {ECO:0000255|HAMAP-Rule:MF_00595};
DE EC=4.1.1.31 {ECO:0000255|HAMAP-Rule:MF_00595};
GN Name=ppc {ECO:0000255|HAMAP-Rule:MF_00595}; OrderedLocusNames=YE0116;
OS Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 /
OS 8081).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=393305;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 13174 / 8081;
RX PubMed=17173484; DOI=10.1371/journal.pgen.0020206;
RA Thomson N.R., Howard S., Wren B.W., Holden M.T.G., Crossman L.,
RA Challis G.L., Churcher C., Mungall K., Brooks K., Chillingworth T.,
RA Feltwell T., Abdellah Z., Hauser H., Jagels K., Maddison M., Moule S.,
RA Sanders M., Whitehead S., Quail M.A., Dougan G., Parkhill J.,
RA Prentice M.B.;
RT "The complete genome sequence and comparative genome analysis of the high
RT pathogenicity Yersinia enterocolitica strain 8081.";
RL PLoS Genet. 2:2039-2051(2006).
CC -!- FUNCTION: Forms oxaloacetate, a four-carbon dicarboxylic acid source
CC for the tricarboxylic acid cycle. {ECO:0000255|HAMAP-Rule:MF_00595}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=oxaloacetate + phosphate = hydrogencarbonate +
CC phosphoenolpyruvate; Xref=Rhea:RHEA:28370, ChEBI:CHEBI:16452,
CC ChEBI:CHEBI:17544, ChEBI:CHEBI:43474, ChEBI:CHEBI:58702; EC=4.1.1.31;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00595};
CC -!- SIMILARITY: Belongs to the PEPCase type 1 family. {ECO:0000255|HAMAP-
CC Rule:MF_00595}.
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DR EMBL; AM286415; CAL10258.1; -; Genomic_DNA.
DR RefSeq; WP_011815299.1; NC_008800.1.
DR RefSeq; YP_001004510.1; NC_008800.1.
DR AlphaFoldDB; A1JI20; -.
DR SMR; A1JI20; -.
DR STRING; 393305.YE0116; -.
DR EnsemblBacteria; CAL10258; CAL10258; YE0116.
DR KEGG; yen:YE0116; -.
DR PATRIC; fig|393305.7.peg.207; -.
DR eggNOG; COG2352; Bacteria.
DR HOGENOM; CLU_006557_2_0_6; -.
DR OMA; PWVFGWT; -.
DR Proteomes; UP000000642; Chromosome.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008964; F:phosphoenolpyruvate carboxylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0015977; P:carbon fixation; IEA:UniProtKB-UniRule.
DR GO; GO:0006107; P:oxaloacetate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR HAMAP; MF_00595; PEPcase_type1; 1.
DR InterPro; IPR021135; PEP_COase.
DR InterPro; IPR022805; PEP_COase_bac/pln-type.
DR InterPro; IPR018129; PEP_COase_Lys_AS.
DR InterPro; IPR033129; PEPCASE_His_AS.
DR InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR PANTHER; PTHR30523; PTHR30523; 1.
DR Pfam; PF00311; PEPcase; 1.
DR PRINTS; PR00150; PEPCARBXLASE.
DR SUPFAM; SSF51621; SSF51621; 1.
DR PROSITE; PS00781; PEPCASE_1; 1.
DR PROSITE; PS00393; PEPCASE_2; 1.
PE 3: Inferred from homology;
KW Carbon dioxide fixation; Lyase; Magnesium.
FT CHAIN 1..879
FT /note="Phosphoenolpyruvate carboxylase"
FT /id="PRO_1000025604"
FT ACT_SITE 137
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
FT ACT_SITE 545
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00595"
SQ SEQUENCE 879 AA; 98363 MW; 5AD46BB12428921F CRC64;
MNEQYSAMRS NVSMLGTLLG DTIKEALGEH ILEKVETIRK LSKSSRAGNE ASRQELLTTL
QNLSNDELLP VARAFSQFLN LTNTAEQYHS ISPHGEAASN PEALAQLFTR LKDKKLSEQD
MRSAVDELSI ELVLTAHPTE ITRRTLIHKL VEVNTCLSQL DHNDLADYER NKIMRRLRQL
VAQSWHTDEI RKIRPSPVDE AKWGFAVVEN SLWEGVPAFL REFNEQLQNS LDYRLPVEAV
PIRFTSWMGG DRDGNPNVTA EITRHVLLLS RWKATDLFLR DIQVLVSELS MSECTPELRE
LAGGEEVLEP YRELMKRVRT QLTNTQAYLE ARLKGERVLP PTDLLVSNDQ LWDPLYACYQ
SLKACGMEII ANGQLLDTLR RVRCFGVPLV RIDVRQESTR HTDAIAELTR YLGLGDYESW
SEADKQAFLI RELNSKRPLV PLKWEPSADT QEVLETCRVI AEAPQGSIAA YVISMAKVPS
DVLAVHLLLK EAGCPFTLPV APLFETLDDL NNADDVMTQL LNIDWYRGLI QGKQMVMIGY
SDSAKDAGVM AASWAQYRAQ DALIKTCEKA GISLTLFHGR GGSIGRGGAP AHAALLSQPP
GSLKGGLRVT EQGEMIRFKF GLPEVTISSL ALYASAVLEA NLLPPPEPKK EWNEVMDILS
DASCEMYRGY VRENPQFVPY FRAATPELEL GKLPLGSRPA KRRPNGGVES LRAIPWIFAW
TQNRLMLPAW LGAGAGLQKA IDAGKKEVLA TMCRDWPFFS TRIGMLEMVF AKADLWLAEY
YDQRLVDKSL WPLGQQLRDQ LEADIKVVLA IANDDHLMAD LPWIAESIAL RNVYTDPLNV
LQAELLHRSR QQENAADACV EQALMVTIAG VAAGMRNTG