ID   Y1149_STRP3             Reviewed;         279 AA.
AC   P0DA54; Q8K6T3;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=DegV domain-containing protein SpyM3_1149;
GN   OrderedLocusNames=SpyM3_1149;
OS   Streptococcus pyogenes serotype M3 (strain ATCC BAA-595 / MGAS315).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=198466;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-595 / MGAS315;
RX   PubMed=12122206; DOI=10.1073/pnas.152298499;
RA   Beres S.B., Sylva G.L., Barbian K.D., Lei B., Hoff J.S., Mammarella N.D.,
RA   Liu M.-Y., Smoot J.C., Porcella S.F., Parkins L.D., Campbell D.S.,
RA   Smith T.M., McCormick J.K., Leung D.Y.M., Schlievert P.M., Musser J.M.;
RT   "Genome sequence of a serotype M3 strain of group A Streptococcus: phage-
RT   encoded toxins, the high-virulence phenotype, and clone emergence.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:10078-10083(2002).
CC   -!- FUNCTION: May bind long-chain fatty acids, such as palmitate, and may
CC       play a role in lipid transport or fatty acid metabolism. {ECO:0000250}.
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DR   EMBL; AE014074; AAM79756.1; -; Genomic_DNA.
DR   RefSeq; WP_011054703.1; NC_004070.1.
DR   AlphaFoldDB; P0DA54; -.
DR   SMR; P0DA54; -.
DR   EnsemblBacteria; AAM79756; AAM79756; SpyM3_1149.
DR   KEGG; spg:SpyM3_1149; -.
DR   HOGENOM; CLU_048251_3_2_9; -.
DR   OMA; EIHAKIN; -.
DR   Proteomes; UP000000564; Chromosome.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1180.10; -; 1.
DR   InterPro; IPR003797; DegV.
DR   InterPro; IPR043168; DegV_C.
DR   Pfam; PF02645; DegV; 1.
DR   TIGRFAMs; TIGR00762; DegV; 1.
DR   PROSITE; PS51482; DEGV; 1.
PE   3: Inferred from homology;
KW   Lipid-binding.
FT   CHAIN           1..279
FT                   /note="DegV domain-containing protein SpyM3_1149"
FT                   /id="PRO_0000209805"
FT   DOMAIN          4..278
FT                   /note="DegV"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00815"
FT   BINDING         62
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
FT   BINDING         95
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
SQ   SEQUENCE   279 AA;  29982 MW;  9DA61537B6323B1C CRC64;
     MGTIKIVTDS SITIEPELIK ALDITVVPLS VMIDSKLYSD NDLKEEGHFL SLMKASKSLP
     KTSQPPVGLF AETYENLVKK GVTDIVAIHL SPALSGTIEA SRQGAEIAET PVTVLDSGFT
     DQAMKFQVVE AAKMAKAGAS LNEILAAVQA IKSKTELYIG VSTLENLVKG GRIGRVTGVL
     SSLLNVKVVM ALKNDELKTL VKGRGNKTFT KWLDSYLAKN SHRPIAEIAI SYAGEASLAL
     TLKERIAAYY NHSISVLETG SIIQTHTGEG AFAVMVRYE