ID   CAPS1_SIFVH             Reviewed;         204 AA.
AC   Q914J4;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   23-FEB-2022, entry version 37.
DE   RecName: Full=Major capsid protein 1;
DE   AltName: Full=MCP1;
GN   Name=SIFV0036;
OS   Sulfolobus islandicus filamentous virus (isolate Iceland/Hveragerdi)
OS   (SIFV).
OC   Viruses; Adnaviria; Zilligvirae; Taleaviricota; Tokiviricetes;
OC   Ligamenvirales; Lipothrixviridae; Betalipothrixvirus.
OX   NCBI_TaxID=654908;
OH   NCBI_TaxID=43080; Sulfolobus islandicus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10662621; DOI=10.1006/viro.1999.0105;
RA   Arnold H.P., Zillig W., Ziese U., Holz I., Crosby M., Utterback T.,
RA   Weidmann J.F., Umayam L.A., Teffera K., Kristjanson J.K., Klenk H.P.,
RA   Nelson K.E., Fraser C.M.;
RT   "A novel lipothrixvirus, SIFV, of the extremely thermophilic crenarchaeon
RT   Sulfolobus.";
RL   Virology 267:252-266(2000).
RN   [2] {ECO:0007744|PDB:6WQ2}
RP   STRUCTURE BY ELECTRON MICROSCOPY (4.00 ANGSTROMS), SUBUNIT, DOMAIN,
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=32759221; DOI=10.1073/pnas.2011125117;
RA   Wang F., Baquero D.P., Beltran L.C., Su Z., Osinski T., Zheng W.,
RA   Prangishvili D., Krupovic M., Egelman E.H.;
RT   "Structures of filamentous viruses infecting hyperthermophilic archaea
RT   explain DNA stabilization in extreme environments.";
RL   Proc. Natl. Acad. Sci. U.S.A. 117:19643-19652(2020).
CC   -!- FUNCTION: Self-assembles to form a helical, filamentous nucleocapsid
CC       mesuring 1980 nm in length and 24 nm in width. Together with capsid
CC       protein 2, wraps arounds the DNA and maintains it in an A-form. Capsid
CC       proteins probably maintain the DNA in A-form by non-specific
CC       desolvation and specific coordination of the DNA phosphate groups by
CC       positively charged residues. This certainly protects the viral DNA
CC       under conditions such as the extreme desiccation of its host.
CC       {ECO:0000269|PubMed:32759221}.
CC   -!- SUBUNIT: Heterodimer composed of major capsid protein 1 and major
CC       capsid protein 2. {ECO:0000269|PubMed:32759221}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:32759221}.
CC   -!- DOMAIN: The N-terminus projects into a DNA groove.
CC       {ECO:0000269|PubMed:32759221}.
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DR   EMBL; AF440571; AAL27747.1; -; Genomic_DNA.
DR   RefSeq; NP_445701.1; NC_003214.2.
DR   PDB; 6WQ2; EM; 4.00 A; a/b/c/d/e/f/g/h/i/j/k/l/m/n/p/r/t=1-204.
DR   PDBsum; 6WQ2; -.
DR   SMR; Q914J4; -.
DR   GeneID; 922344; -.
DR   KEGG; vg:922344; -.
DR   Proteomes; UP000007017; Genome.
DR   GO; GO:0019029; C:helical viral capsid; IDA:UniProtKB.
DR   GO; GO:0003677; F:DNA binding; IDA:UniProtKB.
PE   1: Evidence at protein level;
KW   3D-structure; DNA-binding; Reference proteome; Virion.
FT   CHAIN           1..204
FT                   /note="Major capsid protein 1"
FT                   /id="PRO_0000385414"
SQ   SEQUENCE   204 AA;  22533 MW;  A8426970EF602A2C CRC64;
     MAGRQSHKKI DVRNDTSTRY KGKLYGIFVN YMGEKYAQQL VENMYSNYND VFVEIYNKMH
     NALRPTLVKL AGAGATFPLW QLVNEAIYAV YLTHKETASF LVTKYVARGV PAMTVKTLLA
     EVGNQLKELV PAVAEQIGSV TLDHTNVVST VDNIVTSMPA LPNSYAGVLM KTKVPTVTPH
     YAGTGTFSSM ESAYKALEDI ERGL