ID   Y1176_CORGB             Reviewed;         278 AA.
AC   A4QD57;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Uncharacterized peptidase cgR_1176;
DE   Flags: Precursor;
GN   OrderedLocusNames=cgR_1176;
OS   Corynebacterium glutamicum (strain R).
OC   Bacteria; Actinobacteria; Corynebacteriales; Corynebacteriaceae;
OC   Corynebacterium.
OX   NCBI_TaxID=340322;
RN   [1] {ECO:0000312|EMBL:BAF54154.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R;
RX   PubMed=17379713; DOI=10.1099/mic.0.2006/003657-0;
RA   Yukawa H., Omumasaba C.A., Nonaka H., Kos P., Okai N., Suzuki N., Suda M.,
RA   Tsuge Y., Watanabe J., Ikeda Y., Vertes A.A., Inui M.;
RT   "Comparative analysis of the Corynebacterium glutamicum group and complete
RT   genome sequence of strain R.";
RL   Microbiology 153:1042-1058(2007).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 33-52, AND SUBCELLULAR LOCATION.
RX   PubMed=19066885; DOI=10.1007/s00253-008-1786-6;
RA   Suzuki N., Watanabe K., Okibe N., Tsuchida Y., Inui M., Yukawa H.;
RT   "Identification of new secreted proteins and secretion of heterologous
RT   amylase by C. glutamicum.";
RL   Appl. Microbiol. Biotechnol. 82:491-500(2009).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:19066885}.
CC   -!- SIMILARITY: Belongs to the peptidase S1 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00274}.
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DR   EMBL; AP009044; BAF54154.1; -; Genomic_DNA.
DR   RefSeq; WP_003858612.1; NC_009342.1.
DR   AlphaFoldDB; A4QD57; -.
DR   SMR; A4QD57; -.
DR   EnsemblBacteria; BAF54154; BAF54154; cgR_1176.
DR   GeneID; 58310215; -.
DR   KEGG; cgt:cgR_1176; -.
DR   HOGENOM; CLU_091277_0_0_11; -.
DR   OMA; NQPEINC; -.
DR   PhylomeDB; A4QD57; -.
DR   Proteomes; UP000006698; Chromosome.
DR   GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.10.10; -; 1.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001314; Peptidase_S1A.
DR   InterPro; IPR001254; Trypsin_dom.
DR   Pfam; PF00089; Trypsin; 1.
DR   PRINTS; PR00722; CHYMOTRYPSIN.
DR   SMART; SM00020; Tryp_SPc; 1.
DR   SUPFAM; SSF50494; SSF50494; 1.
DR   PROSITE; PS50240; TRYPSIN_DOM; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Hydrolase; Protease; Secreted;
KW   Serine protease; Signal.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000269|PubMed:19066885"
FT   CHAIN           33..278
FT                   /note="Uncharacterized peptidase cgR_1176"
FT                   /evidence="ECO:0000269|PubMed:19066885"
FT                   /id="PRO_0000392966"
FT   DOMAIN          33..236
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000250|UniProtKB:P07288,
FT                   ECO:0000255|PROSITE-ProRule:PRU00274"
FT   ACT_SITE        74
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P07288,
FT                   ECO:0000255|PROSITE-ProRule:PRU00274"
FT   ACT_SITE        123
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P07288,
FT                   ECO:0000255|PROSITE-ProRule:PRU00274"
FT   ACT_SITE        189
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250|UniProtKB:P07288,
FT                   ECO:0000255|PROSITE-ProRule:PRU00274"
FT   DISULFID        59..75
FT                   /evidence="ECO:0000250|UniProtKB:Q6H321,
FT                   ECO:0000255|PROSITE-ProRule:PRU00274"
SQ   SEQUENCE   278 AA;  28296 MW;  02509866DC90616E CRC64;
     MSSASFTTKA LSVLAALTAA SAPLVAASPA HALANARNVT GSSTTSDSIV RLHIGNTACT
     GTMITPTWAI TARHCIPEDG IAGAAIGSST LSQFQQVSQA ILHPTADLAL VELPNQASSN
     TVDLYGAHVQ PGENGQAAGW GGYSAFGQNV AQQADVQIQR RVVNVPSPDR TAVLLEGTVS
     NGRLVPGDSG GPLYINGQLA GVLSMSTDVE NDALDGTVGW YIPVAEHAEW IAYYTGKHIA
     PIAGAPAELV DATANPTFIP APQPFTGSSI GGWALGSS