ID   Y1176_MYCLE             Reviewed;         119 AA.
AC   P54133;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Uncharacterized protein ML1176;
GN   OrderedLocusNames=ML1176; ORFNames=B1549_F2_59, MLCB1701.02c;
OS   Mycobacterium leprae (strain TN).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=272631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Smith D.R., Robison K.;
RL   Submitted (SEP-1994) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TN;
RX   PubMed=11234002; DOI=10.1038/35059006;
RA   Cole S.T., Eiglmeier K., Parkhill J., James K.D., Thomson N.R.,
RA   Wheeler P.R., Honore N., Garnier T., Churcher C.M., Harris D.E.,
RA   Mungall K.L., Basham D., Brown D., Chillingworth T., Connor R.,
RA   Davies R.M., Devlin K., Duthoy S., Feltwell T., Fraser A., Hamlin N.,
RA   Holroyd S., Hornsby T., Jagels K., Lacroix C., Maclean J., Moule S.,
RA   Murphy L.D., Oliver K., Quail M.A., Rajandream M.A., Rutherford K.M.,
RA   Rutter S., Seeger K., Simon S., Simmonds M., Skelton J., Squares R.,
RA   Squares S., Stevens K., Taylor K., Whitehead S., Woodward J.R.,
RA   Barrell B.G.;
RT   "Massive gene decay in the leprosy bacillus.";
RL   Nature 409:1007-1011(2001).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.tuberculosis Rv1342c. {ECO:0000305}.
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DR   EMBL; U00014; AAA50901.1; -; Genomic_DNA.
DR   EMBL; AL049191; CAB39142.1; -; Genomic_DNA.
DR   EMBL; AL583921; CAC31557.1; -; Genomic_DNA.
DR   PIR; S72786; S72786.
DR   RefSeq; NP_301858.1; NC_002677.1.
DR   RefSeq; WP_010908182.1; NC_002677.1.
DR   AlphaFoldDB; P54133; -.
DR   SMR; P54133; -.
DR   STRING; 272631.ML1176; -.
DR   EnsemblBacteria; CAC31557; CAC31557; CAC31557.
DR   KEGG; mle:ML1176; -.
DR   PATRIC; fig|272631.5.peg.2133; -.
DR   Leproma; ML1176; -.
DR   eggNOG; ENOG50330UF; Bacteria.
DR   HOGENOM; CLU_120964_1_2_11; -.
DR   OMA; TRYRVMA; -.
DR   Proteomes; UP000000806; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR023845; DUF3817_TM.
DR   Pfam; PF12823; DUF3817; 1.
DR   TIGRFAMs; TIGR03954; integ_memb_HG; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..119
FT                   /note="Uncharacterized protein ML1176"
FT                   /id="PRO_0000103816"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        55..75
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        80..100
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   119 AA;  13792 MW;  6C66CE665159BF0E CRC64;
     MTRPETPQAP DFDFEKSRTA LLGYRIMAWT TGIWLIALCY EIVSHLVFHH EIRWIEVVHG
     WVYFVYVLTA FNLAIKVRWP IGKTVGVLLA GTVPLLGIIV EHFQTKDVKT RFGLRHSRT