ID   CAPS1_SPV1              Reviewed;         181 AA.
AC   A0A1W6I187;
DT   29-SEP-2021, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2017, sequence version 1.
DT   23-FEB-2022, entry version 10.
DE   RecName: Full=Capsid protein VP4 {ECO:0000312|EMBL:ARM37825.1};
GN   ORFNames=ORF43 {ECO:0000303|PubMed:31636205};
OS   Sulfolobus polyhedral virus 1 (SPV1).
OC   Viruses; Portogloboviridae; Alphaportoglobovirus.
OX   NCBI_TaxID=1982658;
OH   NCBI_TaxID=2284; Sulfolobus.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S14 {ECO:0000312|EMBL:ARM37825.1};
RX   PubMed=28424284; DOI=10.1128/jvi.00589-17;
RA   Liu Y., Ishino S., Ishino Y., Pehau-Arnaudet G., Krupovic M.,
RA   Prangishvili D.;
RT   "A novel type of polyhedral viruses infecting hyperthermophilic archaea.";
RL   J. Virol. 0:0-0(2017).
RN   [2] {ECO:0007744|PDB:6OJ0}
RP   STRUCTURE BY ELECTRON MICROSCOPY (3.70 ANGSTROMS), FUNCTION, AND
RP   SUBCELLULAR LOCATION.
RX   PubMed=31636205; DOI=10.1073/pnas.1908242116;
RA   Wang F., Liu Y., Su Z., Osinski T., de Oliveira G.A.P., Conway J.F.,
RA   Schouten S., Krupovic M., Prangishvili D., Egelman E.H.;
RT   "A packing for A-form DNA in an icosahedral virus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 116:22591-22597(2019).
CC   -!- FUNCTION: VP4 self-assembles to form, together with capsid protein
CC       VP10, an icosahedral caspid of 87 nm in diameter, with a T=43 symmetry
CC       and composed of 420 hexamers and 12 pentamers (PubMed:31636205). VP4
CC       proteins arrange into hexons, while VP10 proteins form the pentameric
CC       densities located at the 5-fold axes in the virion (PubMed:31636205).
CC       The stoichiometry of VP4:VP10 is 42:1 (PubMed:31636205).
CC       {ECO:0000269|PubMed:31636205}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:31636205}.
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DR   EMBL; KY780159; ARM37825.1; -; Genomic_DNA.
DR   PDB; 6OJ0; EM; 3.70 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/a/b/c/d/e/f=1-181.
DR   PDBsum; 6OJ0; -.
DR   SMR; A0A1W6I187; -.
DR   Proteomes; UP000224527; Genome.
DR   GO; GO:0019030; C:icosahedral viral capsid; IDA:UniProtKB.
PE   1: Evidence at protein level;
KW   3D-structure; Capsid protein; Reference proteome; Virion.
FT   CHAIN           1..181
FT                   /note="Capsid protein VP4"
FT                   /id="PRO_0000453898"
SQ   SEQUENCE   181 AA;  19387 MW;  B9B8857704168249 CRC64;
     MSESVTQQVF NFAVTKSQPF GGYVYSTNLT ASTSSAVTST QLTPLNLSIT LGQITLSGNS
     LVIPATQIWY LTDAYVSVPD YTNITNGAEA DGVILIYKDG VKLMLTTPLI SSMSISNPAR
     THLAQAVKYS PQSILTMYFN PTKPATASTS YPNTVYFTVV VVDFSYAQNP ARAVVSANAV
     M