ID   Y117_METST              Reviewed;         346 AA.
AC   Q2NHU7;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=UPF0219 protein Msp_0117 {ECO:0000255|HAMAP-Rule:MF_01409};
GN   OrderedLocusNames=Msp_0117;
OS   Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 /
OS   MCB-3).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanosphaera.
OX   NCBI_TaxID=339860;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3;
RX   PubMed=16385054; DOI=10.1128/jb.188.2.642-658.2006;
RA   Fricke W.F., Seedorf H., Henne A., Kruer M., Liesegang H., Hedderich R.,
RA   Gottschalk G., Thauer R.K.;
RT   "The genome sequence of Methanosphaera stadtmanae reveals why this human
RT   intestinal archaeon is restricted to methanol and H2 for methane formation
RT   and ATP synthesis.";
RL   J. Bacteriol. 188:642-658(2006).
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. UPF0219 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01409}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000102; ABC56536.1; -; Genomic_DNA.
DR   RefSeq; WP_011405735.1; NC_007681.1.
DR   AlphaFoldDB; Q2NHU7; -.
DR   SMR; Q2NHU7; -.
DR   STRING; 339860.Msp_0117; -.
DR   EnsemblBacteria; ABC56536; ABC56536; Msp_0117.
DR   GeneID; 41324689; -.
DR   KEGG; mst:Msp_0117; -.
DR   eggNOG; arCOG01767; Archaea.
DR   HOGENOM; CLU_039592_7_0_2; -.
DR   OMA; YAKHKGK; -.
DR   OrthoDB; 12601at2157; -.
DR   Proteomes; UP000001931; Chromosome.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:InterPro.
DR   Gene3D; 3.40.47.10; -; 1.
DR   HAMAP; MF_01409; UPF0219; 1.
DR   InterPro; IPR013747; ACP_syn_III_C.
DR   InterPro; IPR004656; FabH-rel.
DR   InterPro; IPR013528; HMG_CoA_synth_N.
DR   InterPro; IPR016039; Thiolase-like.
DR   Pfam; PF08541; ACP_syn_III_C; 1.
DR   Pfam; PF01154; HMG_CoA_synt_N; 1.
DR   SUPFAM; SSF53901; SSF53901; 2.
DR   TIGRFAMs; TIGR00748; HMG_CoA_syn_Arc; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..346
FT                   /note="UPF0219 protein Msp_0117"
FT                   /id="PRO_1000068444"
SQ   SEQUENCE   346 AA;  36971 MW;  81C64015A46BF68B CRC64;
     MTGIVGYGAH IPSYRIKVEE IAKVWGDDPK SISKGLVVNQ KSVPGPDEDT ITISVEAARR
     ALQRAEIDPQ DIGAIYVGSE SHPYAVKPTA TIVADAIRAS PNLTAADLEF ACKAGTAGIQ
     AAVGLVKSGM IKYGLAIGAD TSQGAPGDAL EYTASAGGAA YIIGEDNTIA DIEHTCSFTT
     DTPDFYRREG QAYPSHGGRF TGQPAYFKHV LGAANRMLEE TGTTAKDYDY AVFHQPNGKF
     YIRVARKLGF TEDQYKQGLL TPNIGNTYSG ATPLGLASIL DIAKPGDKIF AVSYGSGAGS
     DAFKITVNDR IEEVRNNAKT LEEIQSKITY VDYATYAKFK GKIKMN