ID   CAPS2_PFV1              Reviewed;         145 AA.
AC   A0A140F3K7;
DT   29-SEP-2021, integrated into UniProtKB/Swiss-Prot.
DT   11-MAY-2016, sequence version 1.
DT   23-FEB-2022, entry version 16.
DE   RecName: Full=Major capsid protein 2 {ECO:0000250|UniProtKB:A0A6M3VWZ7};
DE   AltName: Full=MCP2 {ECO:0000250|UniProtKB:A0A6M3VWZ7};
DE   AltName: Full=Major capsid protein VP2 {ECO:0000303|PubMed:26884161};
OS   Pyrobaculum filamentous virus 1 (PFV1).
OC   Viruses; Adnaviria; Zilligvirae; Taleaviricota; Tokiviricetes;
OC   Primavirales; Tristromaviridae; Alphatristromavirus;
OC   Alphatristromavirus PFV1.
OX   NCBI_TaxID=1805492;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND SUBCELLULAR LOCATION.
RC   STRAIN=1 {ECO:0000312|EMBL:AML61167.1};
RX   PubMed=26884161; DOI=10.1073/pnas.1518929113;
RA   Rensen E.I., Mochizuki T., Quemin E., Schouten S., Krupovic M.,
RA   Prangishvili D.;
RT   "A virus of hyperthermophilic archaea with a unique architecture among DNA
RT   viruses.";
RL   Proc. Natl. Acad. Sci. U.S.A. 113:2478-2483(2016).
CC   -!- FUNCTION: Self-assembles to form a helical, filamentous nucleocapsid.
CC       Together with capsid protein 2, wraps arounds the DNA and maintains it
CC       in an A-form. Capsid proteins probably maintain the DNA in A-form by
CC       non-specific desolvation and specific coordination of the DNA phosphate
CC       groups by positively charged residues. This certainly protects the
CC       viral DNA under conditions such as the extreme desiccation of its host.
CC       {ECO:0000250|UniProtKB:A0A6M3VWZ7}.
CC   -!- SUBUNIT: Heterodimer composed of major capsid protein 1 and major
CC       capsid protein 2. {ECO:0000250|UniProtKB:A0A6M3VWZ7}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:26884161}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KU307456; AML61167.1; -; Genomic_DNA.
DR   RefSeq; YP_009237237.1; NC_029548.1.
DR   SMR; A0A140F3K7; -.
DR   GeneID; 30313573; -.
DR   KEGG; vg:30313573; -.
DR   Proteomes; UP000202991; Genome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Disulfide bond; DNA-binding; Reference proteome; Virion.
FT   CHAIN           1..145
FT                   /note="Major capsid protein 2"
FT                   /id="PRO_0000453810"
FT   DISULFID        96..107
FT                   /evidence="ECO:0000250|UniProtKB:A0A6M3VWZ7"
SQ   SEQUENCE   145 AA;  15235 MW;  565FB86BE2FB9C56 CRC64;
     MSVEVYRQKI EKGGYSAAYE ATRRYERGEI EVLSWSSRWE SAWSKFGEAV KALGKIEGAP
     RALVIAKVQE ALAYMSKPLP NMKLAMAAAV QAVRACEQLP GMNRERCLDA VAGALGVAKD
     WIRREMTGGG GGGGGGGGGG GGAVV