ID   Y1187_METTH             Reviewed;          99 AA.
AC   O27255;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=UPF0045 protein MTH_1187;
GN   OrderedLocusNames=MTH_1187;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
RN   [2]
RP   X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS).
RX   PubMed=12866058; DOI=10.1002/prot.10443;
RA   Tao X., Khayat R., Christendat D., Savchenko A., Xu X.,
RA   Goldsmith-Fischman S., Honig B., Edwards A., Arrowsmith C.H., Tong L.;
RT   "Crystal structures of MTH1187 and its yeast ortholog YBL001c.";
RL   Proteins 52:478-480(2003).
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SIMILARITY: Belongs to the UPF0045 family. {ECO:0000305}.
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DR   EMBL; AE000666; AAB85676.1; -; Genomic_DNA.
DR   PIR; C69025; C69025.
DR   RefSeq; WP_010876811.1; NC_000916.1.
DR   PDB; 1LXN; X-ray; 2.30 A; A/B/C/D=1-99.
DR   PDBsum; 1LXN; -.
DR   AlphaFoldDB; O27255; -.
DR   SMR; O27255; -.
DR   EnsemblBacteria; AAB85676; AAB85676; MTH_1187.
DR   GeneID; 24854310; -.
DR   KEGG; mth:MTH_1187; -.
DR   PATRIC; fig|187420.15.peg.1165; -.
DR   HOGENOM; CLU_137479_3_1_2; -.
DR   OMA; EYETNPM; -.
DR   EvolutionaryTrace; O27255; -.
DR   Proteomes; UP000005223; Chromosome.
DR   Gene3D; 3.30.70.930; -; 1.
DR   InterPro; IPR029756; MTH1187/YkoF-like.
DR   InterPro; IPR002767; Thiamine_BP.
DR   Pfam; PF01910; Thiamine_BP; 1.
DR   SUPFAM; SSF89957; SSF89957; 1.
DR   TIGRFAMs; TIGR00106; TIGR00106; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome.
FT   CHAIN           1..99
FT                   /note="UPF0045 protein MTH_1187"
FT                   /id="PRO_0000147629"
FT   STRAND          2..12
FT                   /evidence="ECO:0007829|PDB:1LXN"
FT   STRAND          14..16
FT                   /evidence="ECO:0007829|PDB:1LXN"
FT   HELIX           19..29
FT                   /evidence="ECO:0007829|PDB:1LXN"
FT   STRAND          35..39
FT                   /evidence="ECO:0007829|PDB:1LXN"
FT   STRAND          42..49
FT                   /evidence="ECO:0007829|PDB:1LXN"
FT   HELIX           50..66
FT                   /evidence="ECO:0007829|PDB:1LXN"
FT   STRAND          70..84
FT                   /evidence="ECO:0007829|PDB:1LXN"
FT   HELIX           88..98
FT                   /evidence="ECO:0007829|PDB:1LXN"
SQ   SEQUENCE   99 AA;  10798 MW;  32D48B66A74C7430 CRC64;
     MITAELTVIP LGTCSTSLSS YVAAAVEALK KLNVRYEISG MGTLLEAEDL DELMEAVKAA
     HEAVLQAGSD RVYTTLKIDD RRDADRGLRD KVESVKEKI