CAPS2_SPV1
ID CAPS2_SPV1 Reviewed; 187 AA.
AC A0A1W6I162;
DT 29-SEP-2021, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2017, sequence version 1.
DT 23-FEB-2022, entry version 10.
DE RecName: Full=Capsid protein VP10;
GN ORFNames=ORF27 {ECO:0000303|PubMed:31636205};
OS Sulfolobus polyhedral virus 1 (SPV1).
OC Viruses; Portogloboviridae; Alphaportoglobovirus.
OX NCBI_TaxID=1982658;
OH NCBI_TaxID=2284; Sulfolobus.
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=S14 {ECO:0000312|EMBL:ARM37809.1};
RX PubMed=28424284; DOI=10.1128/jvi.00589-17;
RA Liu Y., Ishino S., Ishino Y., Pehau-Arnaudet G., Krupovic M.,
RA Prangishvili D.;
RT "A novel type of polyhedral viruses infecting hyperthermophilic archaea.";
RL J. Virol. 0:0-0(2017).
RN [2]
RP STRUCTURE BY ELECTRON MICROSCOPY (3.70 ANGSTROMS), DISULFIDE BONDS,
RP FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=31636205; DOI=10.1073/pnas.1908242116;
RA Wang F., Liu Y., Su Z., Osinski T., de Oliveira G.A.P., Conway J.F.,
RA Schouten S., Krupovic M., Prangishvili D., Egelman E.H.;
RT "A packing for A-form DNA in an icosahedral virus.";
RL Proc. Natl. Acad. Sci. U.S.A. 116:22591-22597(2019).
CC -!- FUNCTION: VP10 self-assembles, together with capsid protein VP4, to
CC form an icosahedral caspid of 87 nm in diameter, with a T=43 symmetry
CC and composed of 420 hexamers and 12 pentamers (PubMed:31636205). VP4
CC proteins arrange into hexons, while VP10 proteins form the pentameric
CC densities located at the 5-fold axes in the virion (PubMed:31636205).
CC The stoichiometry of VP4:VP10 is 42:1 (PubMed:31636205).
CC {ECO:0000269|PubMed:31636205}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:31636205}.
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DR EMBL; KY780159; ARM37809.1; -; Genomic_DNA.
DR PDB; 6OJ0; EM; 3.70 A; Z=1-187.
DR PDBsum; 6OJ0; -.
DR SMR; A0A1W6I162; -.
DR Proteomes; UP000224527; Genome.
DR GO; GO:0019030; C:icosahedral viral capsid; IDA:UniProtKB.
PE 1: Evidence at protein level;
KW 3D-structure; Capsid protein; Disulfide bond; Reference proteome; Virion.
FT CHAIN 1..187
FT /note="Capsid protein VP10"
FT /id="PRO_0000453899"
FT DISULFID 45..51
FT /evidence="ECO:0007744|PDB:6OJ0"
SQ SEQUENCE 187 AA; 20608 MW; C08E5CE2BD95551B CRC64;
MLSLDNYSYV HNITTQTNID LSSQQTIHLA SINGKGYIIF LRFFCEGSSA CFTNVKFSVK
ANGLVLYSFR YIQLLELGQA IATAIPSSSQ GFSTLLSNYN VLISSPIGTL PQLTLYDSYD
NRYGAMLQPA FPLPFVNTLS LDVDILPVSQ SSYDPIPYSL NDNQISTNAP TGKGNISIEY
LLYNCLV