ID   Y1196_METJA             Reviewed;         366 AA.
AC   Q58596;
DT   24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Putative amino-acid transporter MJ1196;
GN   OrderedLocusNames=MJ1196;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC       superfamily. {ECO:0000305}.
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DR   EMBL; L77117; AAB99200.1; -; Genomic_DNA.
DR   PIR; C64449; C64449.
DR   RefSeq; WP_010870708.1; NC_000909.1.
DR   AlphaFoldDB; Q58596; -.
DR   SMR; Q58596; -.
DR   STRING; 243232.MJ_1196; -.
DR   EnsemblBacteria; AAB99200; AAB99200; MJ_1196.
DR   GeneID; 1452091; -.
DR   KEGG; mja:MJ_1196; -.
DR   eggNOG; arCOG00009; Archaea.
DR   HOGENOM; CLU_743174_0_0_2; -.
DR   InParanoid; Q58596; -.
DR   OMA; FAYDGWL; -.
DR   OrthoDB; 15038at2157; -.
DR   PhylomeDB; Q58596; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015655; F:alanine:sodium symporter activity; IEA:InterPro.
DR   InterPro; IPR002293; AA/rel_permease1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   Pfam; PF13520; AA_permease_2; 1.
DR   PRINTS; PR00175; NAALASMPORT.
PE   3: Inferred from homology;
KW   Amino-acid transport; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..366
FT                   /note="Putative amino-acid transporter MJ1196"
FT                   /id="PRO_0000054254"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        111..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        173..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        205..225
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        247..267
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        314..334
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        346..366
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   366 AA;  40470 MW;  450E9B5DC8EF4C80 CRC64;
     MGHLTLKDAV FLTITSIVGG GIFVLSPLTY LLFGKSIIWG WALLIFVSLI MASPFAYAST
     KISESGGVYK FVMKILGREI GVFSAYILWL SGVFALSGVV SFFEIVFNTK FNVSYVGLCL
     IVILTALILG GLRIVGNFVR IFGILTITII LYIVFSNGIK IDSIGEFNLK NAILTIYFGL
     WTATGWEGIT MPLSAFKNQK AIAYGLLVGT FIIGVLYLLF SLTIVSLNVK TNNLDEILKI
     LIGDNLFLLA GMLLIISSCA FSVLFTLSYM PYGMGKDRIF PKAFIKLRKE IPYYGVILNT
     LLVIILLIFD AKTLVDMSMF STLIAYFLLY LAVFKESSGK IKAISLISML ITGLLILFRV
     YNFIIL