ID   Y1201_STRP1             Reviewed;         113 AA.
AC   P67253; Q48YN8; Q99ZK0;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 124.
DE   RecName: Full=UPF0122 protein SPy_1201/M5005_Spy0916;
GN   OrderedLocusNames=SPy_1201, M5005_Spy0916;
OS   Streptococcus pyogenes serotype M1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX   PubMed=11296296; DOI=10.1073/pnas.071559398;
RA   Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA   Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA   Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA   Clifton S.W., Roe B.A., McLaughlin R.E.;
RT   "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX   PubMed=16088826; DOI=10.1086/432514;
RA   Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA   Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA   Musser J.M.;
RT   "Evolutionary origin and emergence of a highly successful clone of serotype
RT   M1 group A Streptococcus involved multiple horizontal gene transfer
RT   events.";
RL   J. Infect. Dis. 192:771-782(2005).
CC   -!- FUNCTION: Might take part in the signal recognition particle (SRP)
CC       pathway. This is inferred from the conservation of its genetic
CC       proximity to ftsY/ffh. May be a regulatory protein (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0122 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE004092; AAK34061.1; -; Genomic_DNA.
DR   EMBL; CP000017; AAZ51534.1; -; Genomic_DNA.
DR   RefSeq; NP_269340.1; NC_002737.2.
DR   PDB; 1S7O; X-ray; 2.31 A; A/B/C=1-113.
DR   PDBsum; 1S7O; -.
DR   AlphaFoldDB; P67253; -.
DR   SMR; P67253; -.
DR   STRING; 1314.HKU360_00960; -.
DR   PaxDb; P67253; -.
DR   EnsemblBacteria; AAK34061; AAK34061; SPy_1201.
DR   KEGG; spy:SPy_1201; -.
DR   KEGG; spz:M5005_Spy0916; -.
DR   PATRIC; fig|160490.10.peg.1048; -.
DR   HOGENOM; CLU_129218_1_1_9; -.
DR   OMA; SIQEWQE; -.
DR   EvolutionaryTrace; P67253; -.
DR   Proteomes; UP000000750; Chromosome.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_00245; UPF0122; 1.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR007394; UPF0122.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR40083; PTHR40083; 1.
DR   Pfam; PF04297; UPF0122; 1.
DR   SUPFAM; SSF88659; SSF88659; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome.
FT   CHAIN           1..113
FT                   /note="UPF0122 protein SPy_1201/M5005_Spy0916"
FT                   /id="PRO_0000211888"
SQ   SEQUENCE   113 AA;  13590 MW;  D82B0620DDA8873B CRC64;
     MNIMEIEKTN RMNALFEFYA ALLTDKQMNY IELYYADDYS LAEIADEFGV SRQAVYDNIK
     RTEKILETYE MKLHMYSDYV VRSEIFDDMI AHYPHDEYLQ EKISILTSID NRE