ID   Y1207_MYCPA             Reviewed;         335 AA.
AC   Q740Y5;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=UPF0353 protein MAP_1207 {ECO:0000255|HAMAP-Rule:MF_01340};
GN   OrderedLocusNames=MAP_1207;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01340};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01340}.
CC   -!- SIMILARITY: Belongs to the UPF0353 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01340}.
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DR   EMBL; AE016958; AAS03524.1; -; Genomic_DNA.
DR   RefSeq; WP_003876099.1; NC_002944.2.
DR   AlphaFoldDB; Q740Y5; -.
DR   SMR; Q740Y5; -.
DR   STRING; 262316.MAP_1207; -.
DR   EnsemblBacteria; AAS03524; AAS03524; MAP_1207.
DR   GeneID; 66694544; -.
DR   KEGG; mpa:MAP_1207; -.
DR   eggNOG; COG2304; Bacteria.
DR   HOGENOM; CLU_024570_2_0_11; -.
DR   OMA; RYFRATD; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.410; -; 1.
DR   HAMAP; MF_01340; UPF0353; 1.
DR   InterPro; IPR022933; UPF0353.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..335
FT                   /note="UPF0353 protein MAP_1207"
FT                   /id="PRO_0000057645"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   DOMAIN          98..294
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
SQ   SEQUENCE   335 AA;  35889 MW;  BCE37C174FE1AF0D CRC64;
     MSLPFLGPMS LSGFEHSWFF LFLLVVAGLA ALYILMQLAR QRRMLRFANM ELLESVAPKR
     PSTWRHLPAI LLVASLVLFT IAMAGPTNDV RIPRNRAVVM LVIDVSQSMR ATDVAPNRMA
     AAQEAAKQFA DELTPGINLG LIAYAGTATV LVSPTTNREA TKNALDKLQF ADRTATGEGI
     FTALQAIATV GAVIGGGDKP PPARIVLFSD GKETMPTNPD NPKGAFTAAR TAKDQGVPIS
     TISFGTPYGF VEINDQRQPV PVDDETLKKV AQLSGGNAYN AASLQELKSV YATLQQQIGY
     ETIKGDASVG WVRLGALVLA LAALTALLIN RRLPT