ID   Y1214_PYRHO             Reviewed;         441 AA.
AC   O58969;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=Uncharacterized ABC transporter extracellular-binding protein PH1214;
DE   Flags: Precursor;
GN   OrderedLocusNames=PH1214; ORFNames=PHBK040;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- FUNCTION: Probably part of a binding-protein-dependent transport system
CC       PH1214/15/16.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- SIMILARITY: Belongs to the bacterial solute-binding protein 1 family.
CC       {ECO:0000305}.
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DR   EMBL; BA000001; BAA30314.1; -; Genomic_DNA.
DR   PIR; H71064; H71064.
DR   RefSeq; WP_010885301.1; NC_000961.1.
DR   AlphaFoldDB; O58969; -.
DR   SMR; O58969; -.
DR   STRING; 70601.3257631; -.
DR   EnsemblBacteria; BAA30314; BAA30314; BAA30314.
DR   GeneID; 1443536; -.
DR   KEGG; pho:PH1214; -.
DR   eggNOG; arCOG00150; Archaea.
DR   OMA; NWLWINP; -.
DR   OrthoDB; 16335at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR006059; SBP.
DR   Pfam; PF01547; SBP_bac_1; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Acetylation; Cell membrane; Lipoprotein; Membrane; Signal; Transport.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           24..441
FT                   /note="Uncharacterized ABC transporter extracellular-
FT                   binding protein PH1214"
FT                   /id="PRO_0000031717"
FT   MOD_RES         24
FT                   /note="N-acetylcysteine"
FT                   /evidence="ECO:0000255"
FT   LIPID           24
FT                   /note="S-archaeol cysteine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   441 AA;  48896 MW;  558D963D816CA7EE CRC64;
     MSRKYLLSLL LVGALVISVV ASGCIGGSQT PTSSPTKTQQ VQELEIYHWW TAGGEKEAFD
     ALAKKFEKKY PNIKIKANPV SGGGGVNLKM VLQSLMLAGK PPDTFQVHAG YEMARYIKAN
     QLTPIDDIWT EDMKKNYPKV IQQMVIFNNH YYAVPINVHR ANVIWYNKQI FKKYGIDPSS
     IKTIDDLFAV AEKLKENGVT PFALGDRNKW PATQVFEVML VAVGGVDYYE KFINGEISAN
     DPTLKKVLEY FVKYVEYSNP DHAAKTWDEA CALVYKGEAA MTLMGDWANG YFKAKGWKPN
     VDYGAIPIPA GVYDLVIDTF VLPAKAAHPN AAKKWLSFIG TVEAQNTFNP IKGSIPPRKD
     APADPYDPIQ KSFIKELSSS ETKLIPSIAH GSAVPEAFLA DLNDIISELA TSKDVNKAAT
     EIINAMKKDL LPNKIKEWHL S