ID   Y1215_PYRHO             Reviewed;         292 AA.
AC   O58968;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   25-MAY-2022, entry version 117.
DE   RecName: Full=Probable ABC transporter permease protein PH1215;
GN   OrderedLocusNames=PH1215; ORFNames=PHBK039;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- FUNCTION: Probably part of a binding-protein-dependent transport system
CC       PH1214/15/16. Probably responsible for the translocation of the
CC       substrate across the membrane.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. MalFG subfamily. {ECO:0000305}.
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DR   EMBL; BA000001; BAA30315.1; -; Genomic_DNA.
DR   PIR; A71065; A71065.
DR   RefSeq; WP_010885302.1; NC_000961.1.
DR   AlphaFoldDB; O58968; -.
DR   SMR; O58968; -.
DR   STRING; 70601.3257632; -.
DR   EnsemblBacteria; BAA30315; BAA30315; BAA30315.
DR   GeneID; 1443537; -.
DR   KEGG; pho:PH1215; -.
DR   eggNOG; arCOG00157; Archaea.
DR   OMA; FMIVVTQ; -.
DR   OrthoDB; 53481at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   CDD; cd06261; TM_PBP2; 1.
DR   Gene3D; 1.10.3720.10; -; 1.
DR   InterPro; IPR000515; MetI-like.
DR   InterPro; IPR035906; MetI-like_sf.
DR   Pfam; PF00528; BPD_transp_1; 1.
DR   SUPFAM; SSF161098; SSF161098; 1.
DR   PROSITE; PS50928; ABC_TM1; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..292
FT                   /note="Probable ABC transporter permease protein PH1215"
FT                   /id="PRO_0000060311"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        106..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        215..235
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   TRANSMEM        261..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT   DOMAIN          68..284
FT                   /note="ABC transmembrane type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ   SEQUENCE   292 AA;  33407 MW;  5B968812C0B89F68 CRC64;
     MRRSPDLPYI ILFLIPALIL IGIFVYFAVV WNIYISFTDW RGLIPSYHFV GLAQYKQLIH
     DPIFWTSLRN NLLLILLFVP GSLLLGLFLA ILLDMKVRFE SGFRTIYVLP FALSFVVTAT
     LWAWMYDPSS GVLNVLFDKL GLDFLKSGWI TDPKIAMYCI IIALIWQFSG YTMIIYLAGI
     RSIPIEQYEG ALIDGASTWQ LYRYIVIPQL TKPTLSAFVV LMVFSLKAFD FIWVLTRGGP
     GTSTFILAIE MYKETFAKTN FAYGAAIATI LLLMALVVVL PYLYWSYKGE ER