Y1216_PYRHO
ID Y1216_PYRHO Reviewed; 275 AA.
AC O58967;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 119.
DE RecName: Full=Probable ABC transporter permease protein PH1216;
GN OrderedLocusNames=PH1216; ORFNames=PHBK038;
OS Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS 100139 / OT-3).
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=70601;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT "Complete sequence and gene organization of the genome of a hyper-
RT thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL DNA Res. 5:55-76(1998).
CC -!- FUNCTION: Probably part of a binding-protein-dependent transport system
CC PH1214/15/16. Probably responsible for the translocation of the
CC substrate across the membrane.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. MalFG subfamily. {ECO:0000305}.
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DR EMBL; BA000001; BAA30316.1; -; Genomic_DNA.
DR PIR; B71065; B71065.
DR RefSeq; WP_010885303.1; NC_000961.1.
DR AlphaFoldDB; O58967; -.
DR SMR; O58967; -.
DR STRING; 70601.3257633; -.
DR EnsemblBacteria; BAA30316; BAA30316; BAA30316.
DR GeneID; 1443538; -.
DR KEGG; pho:PH1216; -.
DR eggNOG; arCOG00159; Archaea.
DR OMA; YIVFQRQ; -.
DR OrthoDB; 46692at2157; -.
DR Proteomes; UP000000752; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 1.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..275
FT /note="Probable ABC transporter permease protein PH1216"
FT /id="PRO_0000060312"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 137..157
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 181..203
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 241..261
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 68..260
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 275 AA; 30683 MW; 826DD280715145AF CRC64;
MRRISPTRFL LYIVLIFLAA WYLLPIWSAI TTSTKTGEQV ALTTPVQFVF PPTFDPYREA
FRELKRPILN SLIFTTFATI FSTILGSIAG FTIAKLVRGR VSRQLLALIS FGIFLPYQSI
LIPLVKIISS LGLYNRILGL ILTHTAYGIP ITTLLFTNYY YEIPDELVEA AKIDGADPWK
IYTKVILPLS KAPFVVTGIY QFTNIWNDYL FGVVLTRGEE AMPATVKLAN LKGSFVANWN
IQMAGALIVA LPTLLIMIAL GKYLIRGYTS GALKG
