ID   Y1217_HAEIN             Reviewed;         913 AA.
AC   P45114;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Probable TonB-dependent receptor HI_1217;
DE   Flags: Precursor;
GN   OrderedLocusNames=HI_1217;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=10675023;
RX   DOI=10.1002/(sici)1522-2683(20000101)21:2<411::aid-elps411>3.0.co;2-4;
RA   Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C.,
RA   Fountoulakis M.;
RT   "Two-dimensional map of the proteome of Haemophilus influenzae.";
RL   Electrophoresis 21:411-429(2000).
CC   -!- FUNCTION: Probable receptor, TonB-dependent.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Peripheral
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TonB-dependent receptor family.
CC       {ECO:0000305}.
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DR   EMBL; L42023; AAC22870.1; -; Genomic_DNA.
DR   PIR; G64110; G64110.
DR   RefSeq; NP_439373.1; NC_000907.1.
DR   RefSeq; WP_005694229.1; NC_000907.1.
DR   AlphaFoldDB; P45114; -.
DR   STRING; 71421.HI_1217; -.
DR   TCDB; 1.B.14.7.3; the outer membrane receptor (omr) family.
DR   EnsemblBacteria; AAC22870; AAC22870; HI_1217.
DR   KEGG; hin:HI_1217; -.
DR   PATRIC; fig|71421.8.peg.1269; -.
DR   eggNOG; COG1629; Bacteria.
DR   eggNOG; COG4206; Bacteria.
DR   HOGENOM; CLU_008287_19_1_6; -.
DR   OMA; QVNIRGM; -.
DR   PhylomeDB; P45114; -.
DR   BioCyc; HINF71421:G1GJ1-1248-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0031230; C:intrinsic component of cell outer membrane; IBA:GO_Central.
DR   GO; GO:0015344; F:siderophore uptake transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0044718; P:siderophore transmembrane transport; IBA:GO_Central.
DR   Gene3D; 2.170.130.10; -; 1.
DR   Gene3D; 2.40.170.20; -; 1.
DR   InterPro; IPR039426; BtuB-like.
DR   InterPro; IPR012910; Plug_dom.
DR   InterPro; IPR037066; Plug_dom_sf.
DR   InterPro; IPR000531; TonB-dep_rcpt_b-brl.
DR   InterPro; IPR036942; TonB_rcpt_b-brl_sf.
DR   PANTHER; PTHR30069; PTHR30069; 1.
DR   Pfam; PF07715; Plug; 1.
DR   Pfam; PF00593; TonB_dep_Rec; 1.
DR   PROSITE; PS01156; TONB_DEPENDENT_REC_2; 1.
PE   1: Evidence at protein level;
KW   Cell outer membrane; Membrane; Receptor; Reference proteome; Signal;
KW   TonB box; Transmembrane; Transmembrane beta strand.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..913
FT                   /note="Probable TonB-dependent receptor HI_1217"
FT                   /id="PRO_0000034793"
FT   MOTIF           896..913
FT                   /note="TonB C-terminal box"
SQ   SEQUENCE   913 AA;  102768 MW;  01BEFDE6D6AEF617 CRC64;
     MKKAIKLNLI TLGLINTIGM TITQAQAEET LGQIDVVEKV ISNDKKPFTE AKAKSTRENV
     FKETQTIDQV IRSIPGAFTQ QDKGSGVVSV NIRGENGLGR VNTMVDGVTQ TFYSTALDSG
     QSGGSSQFGA AIDPNFIAGV DVNKSNFSGA SGINALAGSA NFRTLGVNDV ITDDKPFGII
     LKGMTGSNAT KSNFMTMAAG RKWLDNGGYV GVVYGYSQRE VSQDYRIGGG ERLASLGQDI
     LAKEKEAYFR NAGYILNPEG QWTPDLSKKH WSCNKPDYQK NGDCSYYRIG SAAKTRREIL
     QELLTNGKKP KDIEKLQKGN DGIEETDKSF ERNKDQYSVA PIEPGSLQSR SRSHLLKFEY
     GDDHQNLGAQ LRTLDNKIGS RKIENRNYQV NYNFNNNSYL DLNLMAAHNI GKTIYPKGGF
     FAGWQVADKL ITKNVANIVD INNSHTFLLP KEIDLKTTLG FNYFTNEYSK NRFPEELSLF
     YNDASHDQGL YSHSKRGRYS GTKSLLPQRS VILQPSGKQK FKTVYFDTAL SKGIYHLNYS
     VNFTHYAFNG EYVGYENTAG QQINEPILHK SGHKKAFNHS ATLSAELSDY FMPFFTYSRT
     HRMPNIQEMF FSQVSNAGVN TALKPEQSDT YQLGFNTYKK GLFTQDDVLG VKLVGYRSFI
     KNYIHNVYGV WWRDGMPTWA ESNGFKYTIA HQNYKPIVKK SGVELEINYD MGRFFANVSY
     AYQRTNQPTN YADASPRPNN ASQEDILKQG YGLSRVSMLP KDYGRLELGT RWFDQKLTLG
     LAARYYGKSK RATIEEEYIN GSRFKKNTLR RENYYAVKKT EDIKKQPIIL DLHVSYEPIK
     DLIIKAEVQN LLDKRYVDPL DAGNDAASQR YYSSLNNSIE CAQDSSACGG SDKTVLYNFA
     RGRTYILSLN YKF