ID   Y1218_STAHJ             Reviewed;         229 AA.
AC   Q4L748;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=UPF0173 metal-dependent hydrolase SH1218 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=SH1218;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; AP006716; BAE04527.1; -; Genomic_DNA.
DR   RefSeq; WP_011275517.1; NC_007168.1.
DR   AlphaFoldDB; Q4L748; -.
DR   SMR; Q4L748; -.
DR   STRING; 279808.SH1218; -.
DR   EnsemblBacteria; BAE04527; BAE04527; SH1218.
DR   GeneID; 58062583; -.
DR   KEGG; sha:SH1218; -.
DR   eggNOG; COG2220; Bacteria.
DR   HOGENOM; CLU_070010_4_1_9; -.
DR   OMA; WHGHSTW; -.
DR   OrthoDB; 767622at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..229
FT                   /note="UPF0173 metal-dependent hydrolase SH1218"
FT                   /id="PRO_0000156386"
SQ   SEQUENCE   229 AA;  25327 MW;  FCDD879DA270FDC2 CRC64;
     MKLSFHGQST IYFEGNGKKV IVDPFISGND KCDLDEQTLD VDYIILTHGH ADHFGDVVEL
     ANRNHATVIG SAELQGYLST YHGVEDVHGM NIGGKAKFDF GSVKYVQAFH SSSFTHEDGI
     PVYLGMPMGL ILEVEGKTIY HMGDTGLFSD MKLIAERHPV DVCFVPIGDN FTMGIDDASY
     AINEFVKPKI SVPVHYNTFP LIEQDPQQFK DAVHEGEVQI LEPGESVSF