CAPSD_AMVYS
ID CAPSD_AMVYS Reviewed; 221 AA.
AC P24264;
DT 01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 2.
DT 03-AUG-2022, entry version 77.
DE RecName: Full=Capsid protein;
DE Short=CP;
DE AltName: Full=Coat protein;
GN ORFNames=ORF3b;
OS Alfalfa mosaic virus (strain YSMV).
OC Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC Martellivirales; Bromoviridae; Alfamovirus.
OX NCBI_TaxID=12325;
OH NCBI_TaxID=4045; Apium graveolens (Celery).
OH NCBI_TaxID=83862; Astragalus glycyphyllos (Wild liquorice).
OH NCBI_TaxID=4072; Capsicum annuum (Capsicum pepper).
OH NCBI_TaxID=41386; Caryopteris incana.
OH NCBI_TaxID=3827; Cicer arietinum (Chickpea) (Garbanzo).
OH NCBI_TaxID=3847; Glycine max (Soybean) (Glycine hispida).
OH NCBI_TaxID=35936; Lablab purpureus (Hyacinth bean) (Dolichos lablab).
OH NCBI_TaxID=4236; Lactuca sativa (Garden lettuce).
OH NCBI_TaxID=3864; Lens culinaris (Lentil) (Cicer lens).
OH NCBI_TaxID=3869; Lupinus.
OH NCBI_TaxID=145753; Malva parviflora (Little mallow) (Cheeseweed mallow).
OH NCBI_TaxID=3879; Medicago sativa (Alfalfa).
OH NCBI_TaxID=4097; Nicotiana tabacum (Common tobacco).
OH NCBI_TaxID=3885; Phaseolus vulgaris (Kidney bean) (French bean).
OH NCBI_TaxID=23113; Philadelphus.
OH NCBI_TaxID=3888; Pisum sativum (Garden pea).
OH NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OH NCBI_TaxID=4113; Solanum tuberosum (Potato).
OH NCBI_TaxID=60916; Trifolium incarnatum (Crimson clover).
OH NCBI_TaxID=3899; Trifolium repens (Creeping white clover).
OH NCBI_TaxID=85293; Viburnum opulus (High-bush cranberry).
OH NCBI_TaxID=3916; Vigna radiata var. radiata (Mung bean) (Phaseolus aureus).
OH NCBI_TaxID=3917; Vigna unguiculata (Cowpea).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX PubMed=2014643; DOI=10.1016/0042-6822(91)90902-n;
RA Neeleman L., der Kuyl A.C., Bol J.F.;
RT "Role of alfalfa mosaic virus coat protein gene in symptom formation.";
RL Virology 181:687-693(1991).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 2-26 IN COMPLEX WITH VIRAL RNA.
RX PubMed=15604410; DOI=10.1126/science.1103399;
RA Guogas L.M., Filman D.J., Hogle J.M., Gehrke L.;
RT "Cofolding organizes alfalfa mosaic virus RNA and coat protein for
RT replication.";
RL Science 306:2108-2111(2004).
CC -!- FUNCTION: Capsid protein. Binds to the to the 3' end of the
CC nonpolyadenylated viral RNA and is involved in viral RNA translation
CC initiation. Probably binds RNA and plays a role in packaging (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the alphamovirus/ilarvirus capsid protein
CC family. {ECO:0000305}.
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DR EMBL; M59241; AAA46288.1; -; Genomic_RNA.
DR PIR; B37948; VCFMYS.
DR PDB; 1XOK; X-ray; 3.00 A; C/D=2-27.
DR PDBsum; 1XOK; -.
DR SMR; P24264; -.
DR EvolutionaryTrace; P24264; -.
DR GO; GO:0039617; C:T=3 icosahedral viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0019013; C:viral nucleocapsid; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006413; P:translational initiation; IEA:InterPro.
DR InterPro; IPR002681; Coat_Ilarvirus.
DR Pfam; PF01787; Ilar_coat; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Acetylation; Capsid protein; Ribonucleoprotein; RNA-binding;
KW T=3 icosahedral capsid protein; Viral nucleoprotein; Virion.
FT INIT_MET 1
FT /note="Removed; by host"
FT /evidence="ECO:0000250"
FT CHAIN 2..221
FT /note="Capsid protein"
FT /id="PRO_0000083192"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylserine; by host"
FT /evidence="ECO:0000250"
FT HELIX 17..26
FT /evidence="ECO:0007829|PDB:1XOK"
SQ SEQUENCE 221 AA; 24352 MW; 693EBF50DA71E682 CRC64;
MSSSQKKAGG KAGKPTKRSQ NYAALRKARL PKPPALKVPV AKPTNTILPQ TGCVWQSLGT
PLSLSSFNGL GVRFLYSFLK DFAGPRILEE DLIYRMVFSI TPSHAGTFCL TDDVTTEDGR
AVAHGNPMQE FPHGAFHANE KFGFELVFTA PTHAGMQNQN FKHSYAVALC LDFDAQPEGS
KNPSYRFNEV WVERKAFPRA GPLRSLITVG LLDEADDLDR H