ID   CAPSD_ANV1              Reviewed;         683 AA.
AC   Q9JGF1;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   23-FEB-2022, entry version 57.
DE   RecName: Full=Capsid polyprotein VP90;
GN   ORFNames=ORF2;
OS   Avian nephritis virus 1 (ANV-1).
OC   Viruses; Riboviria; Orthornavirae; Pisuviricota; Stelpaviricetes;
OC   Stellavirales; Astroviridae; Avastrovirus.
OX   NCBI_TaxID=336960;
OH   NCBI_TaxID=9031; Gallus gallus (Chicken).
OH   NCBI_TaxID=9103; Meleagris gallopavo (Wild turkey).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA].
RX   PubMed=10954549; DOI=10.1128/jvi.74.18.8487-8493.2000;
RA   Imada T., Yamaguchi S., Mase M., Tsukamoto K., Kubo M., Morooka A.;
RT   "Avian nephritis virus (ANV) as a new member of the family Astroviridae and
RT   construction of infectious ANV cDNA.";
RL   J. Virol. 74:8487-8493(2000).
CC   -!- FUNCTION: Capsid polyprotein VP90: self-assembles to form an
CC       icosahedral T=3 capsid. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}.
CC   -!- PTM: Specific enzymatic cleavages in vivo yield mature protein(s). VP90
CC       undergoes a cascade of proteolytic cleavages presumably mediated by
CC       host caspases and extracellular proteases (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the astroviridae capsid polyprotein family.
CC       {ECO:0000305}.
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DR   EMBL; AB033998; BAA92849.1; -; Genomic_RNA.
DR   SMR; Q9JGF1; -.
DR   Proteomes; UP000007440; Genome.
DR   GO; GO:0039615; C:T=1 icosahedral viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0039573; P:suppression by virus of host complement activation; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.20; -; 1.
DR   InterPro; IPR004337; Capsid_astroviral.
DR   InterPro; IPR029053; Viral_coat.
DR   Pfam; PF03115; Astro_capsid_N; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Host-virus interaction;
KW   Inhibition of host complement factors by virus;
KW   T=1 icosahedral capsid protein; Viral immunoevasion; Virion.
FT   CHAIN           1..683
FT                   /note="Capsid polyprotein VP90"
FT                   /id="PRO_0000320244"
FT   REGION          1..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          391..413
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..36
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   683 AA;  73909 MW;  0685EE3D229405AC CRC64;
     MAGGATAPAG AKPKQPKQKQ KKPSSQARKK PSQKQKAMKP VKQELRKVEK QVRVLKARTN
     GPKVNDTMKT TVTVGTLVGQ TQSGLNRQLR VSFNPLLMKS TEGGSTTPLS IRASMYEMWK
     PLSVEIFATP LSGFSSVVGS VGFMVITLNG LEASADSIDT IKARRHVQMA LGRPYRLKLS
     ARELAGPREG WWLVDTSEAP ADAYGPAVDL MLAYATENLL GTSSGSTTSY TGTLWQVEMR
     VTYAFSTYNP KPGLQTLVSQ SITGGQTVTI QPSPDDGSLI MTTNSQQVLA LLTPRVAGQR
     KGKSQTIWAI AGSAVDAAAT VLGPWGYLLK GGFWLVRLIF GGSSARNTTT RQYQIYPSVE
     SALTDQPIFG NSTGTQSVTV PICHITEVVN PNAESNNLPP PTTGAQPQPQ PPAPIEEILL
     PLAELTGQPG VPPLYTFDGS SYTPPTNWLG STILLTGIPA HKRVTGNLAK FGVTNLQMSK
     VAATALEIYD FTDFGVFFGT GSYLSEGGIH TGKTLIYSLM SGQTPNPWLA ANQSGTTWYM
     PSWAGFPQPG QGDYFLQMQD VTDTTTHTTS VNVYFLVAYR QSRRLIAFFN TGGTARPAPT
     SMLCLYNVDC GRAPQTPYPT FQSTLQSLNQ IGVDAKSDPD SDDDISLAGS VIGDEFDSVD
     HLEREREDLM RRLRDLDLRR FQI