Y1221_YERPE
ID Y1221_YERPE Reviewed; 384 AA.
AC Q7CH99; Q74WF4;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Uncharacterized MFS-type transporter YPO1221/y2967/YP_0917;
GN OrderedLocusNames=YPO1221, y2967, YP_0917; ORFNames=YPO1220;
OS Yersinia pestis.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=632;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CO-92 / Biovar Orientalis;
RX PubMed=11586360; DOI=10.1038/35097083;
RA Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA Stevens K., Whitehead S., Barrell B.G.;
RT "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL Nature 413:523-527(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIM10+ / Biovar Mediaevalis;
RX PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT "Genome sequence of Yersinia pestis KIM.";
RL J. Bacteriol. 184:4601-4611(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=91001 / Biovar Mediaevalis;
RX PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA Wang J., Huang P., Yang R.;
RT "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT avirulent to humans.";
RL DNA Res. 11:179-197(2004).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000305}.
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DR EMBL; AL590842; CAL19881.1; -; Genomic_DNA.
DR EMBL; AE009952; AAM86518.1; -; Genomic_DNA.
DR EMBL; AE017042; AAS61173.1; -; Genomic_DNA.
DR PIR; AG0149; AG0149.
DR RefSeq; WP_002210825.1; NZ_WUCM01000017.1.
DR RefSeq; YP_002346253.1; NC_003143.1.
DR AlphaFoldDB; Q7CH99; -.
DR SMR; Q7CH99; -.
DR STRING; 214092.YPO1221; -.
DR PaxDb; Q7CH99; -.
DR EnsemblBacteria; AAM86518; AAM86518; y2967.
DR EnsemblBacteria; AAS61173; AAS61173; YP_0917.
DR GeneID; 66842306; -.
DR KEGG; ype:YPO1221; -.
DR KEGG; ypk:y2967; -.
DR KEGG; ypm:YP_0917; -.
DR PATRIC; fig|214092.21.peg.1524; -.
DR eggNOG; COG2223; Bacteria.
DR HOGENOM; CLU_035309_1_0_6; -.
DR OMA; WAPLVPY; -.
DR Proteomes; UP000000815; Chromosome.
DR Proteomes; UP000001019; Chromosome.
DR Proteomes; UP000002490; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; -; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..384
FT /note="Uncharacterized MFS-type transporter
FT YPO1221/y2967/YP_0917"
FT /id="PRO_0000273017"
FT TRANSMEM 22..42
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 106..126
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 164..184
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 202..222
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 240..260
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 299..319
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 327..347
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 352..372
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 384 AA; 39368 MW; 13F7CCD21FFDEDE0 CRC64;
MSTKIHQQAV QPGISQQVST RLAFFIAGLG MAAWAPLVPF AKARIGLNDA SLGLLLLCIG
IGSMLAMPLT GVLTAKWGCR AVILLAGAVL CLDLPLLVLM NTPATMAIAL LVFGAAMGII
DVAMNIQAVI VEKASGRAMM SGFHGLFSVG GIVGAGGVSA LLWLGLNPLT AIMATVVLMI
ILLLAANKNL LRGSGEPHDG PLFVFPRGWV MFIGFLCFVM FLAEGSMLDW SAVFLTTLRG
MSPSQAGMGY AVFAIAMTLG RLNGDRIVNG LGRYKVLLGG SLCSAIGIII AISIDSSMAA
IIGFMLVGFG ASNVVPILFT AAGNQTVMPA NLAVASITTI GYAGILAGPA AIGFIAQLSS
LSVAFGCVAL LLLTVAASAR AVTR
