ID   Y1229_BACTN             Reviewed;         555 AA.
AC   Q8A8D8;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Uncharacterized transporter BT_1229;
GN   OrderedLocusNames=BT_1229;
OS   Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 /
OS   CCUG 10774 / NCTC 10582 / VPI-5482 / E50).
OC   Bacteria; Bacteroidetes; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=226186;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 /
RC   VPI-5482 / E50;
RX   PubMed=12663928; DOI=10.1126/science.1080029;
RA   Xu J., Bjursell M.K., Himrod J., Deng S., Carmichael L.K., Chiang H.C.,
RA   Hooper L.V., Gordon J.I.;
RT   "A genomic view of the human-Bacteroides thetaiotaomicron symbiosis.";
RL   Science 299:2074-2076(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family.
CC       {ECO:0000305}.
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DR   EMBL; AE015928; AAO76336.1; -; Genomic_DNA.
DR   RefSeq; NP_810142.1; NC_004663.1.
DR   RefSeq; WP_008763411.1; NZ_UYXG01000007.1.
DR   AlphaFoldDB; Q8A8D8; -.
DR   SMR; Q8A8D8; -.
DR   STRING; 226186.BT_1229; -.
DR   PaxDb; Q8A8D8; -.
DR   PRIDE; Q8A8D8; -.
DR   EnsemblBacteria; AAO76336; AAO76336; BT_1229.
DR   GeneID; 60927207; -.
DR   KEGG; bth:BT_1229; -.
DR   PATRIC; fig|226186.12.peg.1255; -.
DR   eggNOG; COG0490; Bacteria.
DR   eggNOG; COG2985; Bacteria.
DR   HOGENOM; CLU_035023_3_1_10; -.
DR   InParanoid; Q8A8D8; -.
DR   OMA; VYPLGMF; -.
DR   Proteomes; UP000001414; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 2.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 2.
DR   SUPFAM; SSF116726; SSF116726; 2.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 2.
DR   PROSITE; PS51202; RCK_C; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..555
FT                   /note="Uncharacterized transporter BT_1229"
FT                   /id="PRO_0000208754"
FT   TRANSMEM        13..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..120
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        157..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        376..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        408..430
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        437..459
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        469..491
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        498..517
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        532..554
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          188..273
FT                   /note="RCK C-terminal 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
FT   DOMAIN          282..366
FT                   /note="RCK C-terminal 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00544"
SQ   SEQUENCE   555 AA;  59617 MW;  1EBD0B1DBAC64477 CRC64;
     MEWLYNLFLE HSALQAVVVL SLISAIGLGL GRVHFWGVSL GVTFVFFAGI LAGHFGLSVD
     PQMLNYAESF GLVIFVYSLG LQVGPGFFSS FRKGGVTLNM LALAVVLLGT LLTVVASYAT
     GVSLPDMVGI LCGATTNTPA LGAAQQTLKQ MGIESSTPAL GCAVAYPMGV IGVILAVLLI
     RKFLVHKEDL EIKEKDDANK TFIAAFQVHN PAIFNKSIKD IAQMSYPKFV ISRLWRDGHV
     SIPTSDKVLK EGDRLLVITA EKNVLALTVL FGEQEENTDW NKEDIDWNAI DSELISQRIV
     VTRPELNGKK LGSLRLRNHY GINISRVYRS GVQLLATPEL ILQLGDRLTV VGEAAAIQNV
     EKVLGNAVKS LKEPNLVVIF IGIVLGLALG AIPFSIPGIS TPVKLGLAGG PIIVGILLGT
     FGPRIHMITY TTRSANLMLR ALGLSMYLAC LGLDAGAHFF DTVFRPEGLL WIALGAGLTI
     IPTVLVGFVA FKIMKIDFGS VSGMLCGSMA NPMALNYAND TIPGDNPSVA YATVYPLCMF
     LRVIIAQVLL MFLLG