ID   Y1233_VIBCH             Reviewed;         129 AA.
AC   Q9KSM3;
DT   29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=UPF0299 membrane protein VC_1233 {ECO:0000255|HAMAP-Rule:MF_01144};
GN   OrderedLocusNames=VC_1233;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01144}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01144}.
CC   -!- SIMILARITY: Belongs to the UPF0299 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01144}.
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DR   EMBL; AE003852; AAF94392.1; -; Genomic_DNA.
DR   PIR; A82227; A82227.
DR   RefSeq; NP_230878.1; NC_002505.1.
DR   AlphaFoldDB; Q9KSM3; -.
DR   STRING; 243277.VC_1233; -.
DR   DNASU; 2614670; -.
DR   EnsemblBacteria; AAF94392; AAF94392; VC_1233.
DR   KEGG; vch:VC_1233; -.
DR   PATRIC; fig|243277.26.peg.1175; -.
DR   eggNOG; COG1380; Bacteria.
DR   HOGENOM; CLU_113736_1_1_6; -.
DR   OMA; MSVMFIP; -.
DR   BioCyc; VCHO:VC1233-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01144; UPF0299; 1.
DR   InterPro; IPR005538; LrgA/CidA.
DR   InterPro; IPR022957; Uncharacterised_UPF0299.
DR   PANTHER; PTHR33931; PTHR33931; 1.
DR   Pfam; PF03788; LrgA; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..129
FT                   /note="UPF0299 membrane protein VC_1233"
FT                   /id="PRO_0000072815"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01144"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01144"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01144"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01144"
SQ   SEQUENCE   129 AA;  13855 MW;  D3DA4331C952EDD9 CRC64;
     MLILLMIKKI AQYCVSMGLI FLCLLAGINL QTWLGIAIPG SIIGLLILFG LMASGLVPVE
     WVKPSATLFI RYMILLFVPI SVGLMVHFDT LLANLAPILA SAIGGTLIVM VTLGLILDRM
     LKKGKKSCG