ID   CAPSD_BCTVC             Reviewed;         254 AA.
AC   P14984; Q91J28;
DT   01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT   18-MAR-2008, sequence version 2.
DT   23-FEB-2022, entry version 81.
DE   RecName: Full=Capsid protein;
DE   AltName: Full=Coat protein;
DE            Short=CP;
GN   ORFNames=V1;
OS   Beet curly top virus (strain California/Logan) (BCTV).
OC   Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Repensiviricetes;
OC   Geplafuvirales; Geminiviridae; Curtovirus.
OX   NCBI_TaxID=268960;
OH   NCBI_TaxID=161934; Beta vulgaris (Sugar beet).
OH   NCBI_TaxID=4071; Capsicum (peppers).
OH   NCBI_TaxID=3650; Cucurbitaceae.
OH   NCBI_TaxID=4005; Linum.
OH   NCBI_TaxID=3885; Phaseolus vulgaris (Kidney bean) (French bean).
OH   NCBI_TaxID=4081; Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OH   NCBI_TaxID=4113; Solanum tuberosum (Potato).
OH   NCBI_TaxID=3562; Spinacia oleracea (Spinach).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Infectious clone pBCT028;
RX   PubMed=16453696; DOI=10.1002/j.1460-2075.1986.tb04424.x;
RA   Stanley J., Markham P.G., Callis R.J., Pinner M.S.;
RT   "The nucleotide sequence of an infectious clone of the geminivirus beet
RT   curly top virus.";
RL   EMBO J. 5:1761-1767(1986).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Bisaro D.M., Hormuzdi S.G.;
RL   Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   IDENTIFICATION.
RX   PubMed=8460493; DOI=10.1006/viro.1993.1199;
RA   Hormuzdi S.G., Bisaro D.M.;
RT   "Genetic analysis of beet curly top virus: evidence for three virion sense
RT   genes involved in movement and regulation of single- and double-stranded
RT   DNA levels.";
RL   Virology 193:900-909(1993).
CC   -!- FUNCTION: Encapsidates the viral genome into characteristic twinned
CC       ('geminate') particles. Binds the genomic viral ssDNA and shuttles it
CC       into and out of the cell nucleus. Plays a role in protection of the
CC       genome from degradation, virus acquisition and transmission by insect
CC       vectors, infectivity, and systemic movement. The CP of monopartite
CC       geminiviruses is absolutely essential for virus movement (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homomultimer. Binds to single-stranded and double-stranded
CC       viral DNA. Interacts (via nuclear localization signal) with host
CC       importin alpha-1a (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250}. Host nucleus {ECO:0000250}.
CC       Note=It is actively transported into the host cell nucleus. It may be
CC       exported out of the nucleus through a nuclear export signal for cell-
CC       to-cell movement and spread (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the geminiviridae capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; M24597; AAA42753.1; -; Genomic_DNA.
DR   EMBL; AF379637; AAK59258.1; -; Genomic_DNA.
DR   PIR; S28362; S28362.
DR   SMR; P14984; -.
DR   Proteomes; UP000006542; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0039615; C:T=1 icosahedral viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR   GO; GO:0075732; P:viral penetration into host nucleus; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.20; -; 1.
DR   InterPro; IPR000143; Gemcoat_MSV.
DR   InterPro; IPR000263; GV_A/BR1_coat.
DR   InterPro; IPR029053; Viral_coat.
DR   Pfam; PF00844; Gemini_coat; 1.
DR   PRINTS; PR00223; GEMCOATARBR1.
DR   PRINTS; PR00226; GEMCOATMSV.
PE   3: Inferred from homology;
KW   Capsid protein; DNA-binding; Host nucleus; Reference proteome;
KW   T=1 icosahedral capsid protein; Viral penetration into host nucleus;
KW   Virion; Virus entry into host cell.
FT   CHAIN           1..254
FT                   /note="Capsid protein"
FT                   /id="PRO_0000222178"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           10..35
FT                   /note="Bipartite nuclear localization signal"
FT                   /evidence="ECO:0000250"
FT   COMPBIAS        1..27
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         89
FT                   /note="R -> K (in strain: Infectious clone pBCT028)"
FT   VARIANT         165
FT                   /note="V -> G (in strain: Infectious clone pBCT028)"
FT   VARIANT         173
FT                   /note="L -> W (in strain: Infectious clone pBCT028)"
SQ   SEQUENCE   254 AA;  29604 MW;  E947F761CCB75456 CRC64;
     MRKYTRNTYT MSQKRKVNPQ SAWPKKRRTS TTSRKYQWRR PVTKNRTLKL KMYDDMLGAG
     GIGSTISNNG MITMLNNYVQ GIGDSQRARN VTVTKHLKFD MALMGSSQFW ETPNYMTQYH
     WIIIDKDVGS VFPTKLSSIF DIPDNGQAMP STYRIRRDMN ERFIVKKKWR THLMSTGTGY
     GGKETYKAPS MPNYKKPMNI NVRNLNMRTI WKDTGGGKYE DVKENALLYV VVNDNTDNTN
     MYATLFGNCR CYFY