ID   Y1242_SYNY3             Reviewed;         536 AA.
AC   P42349;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Uncharacterized methyltransferase sll1242;
DE            EC=2.1.1.-;
DE   AltName: Full=ORF N;
GN   OrderedLocusNames=sll1242;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 291-536.
RX   PubMed=8467083; DOI=10.1007/bf00027122;
RA   Malakhov M.P., Wada H., Los D.A., Sakamoto T., Murata N.;
RT   "Structure of a cyanobacterial gene encoding the 50S ribosomal protein
RT   L9.";
RL   Plant Mol. Biol. 21:913-918(1993).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000305};
CC       Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3
CC       cysteines and an exchangeable S-adenosyl-L-methionine. {ECO:0000305};
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DR   EMBL; BA000022; BAA18175.1; -; Genomic_DNA.
DR   EMBL; D10716; BAA38817.1; -; Genomic_DNA.
DR   PIR; S75614; S75614.
DR   AlphaFoldDB; P42349; -.
DR   SMR; P42349; -.
DR   STRING; 1148.1653260; -.
DR   PaxDb; P42349; -.
DR   PRIDE; P42349; -.
DR   EnsemblBacteria; BAA18175; BAA18175; BAA18175.
DR   KEGG; syn:sll1242; -.
DR   eggNOG; COG1032; Bacteria.
DR   InParanoid; P42349; -.
DR   OMA; IVIWRQG; -.
DR   PhylomeDB; P42349; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.30.20; -; 1.
DR   InterPro; IPR006158; Cobalamin-bd.
DR   InterPro; IPR025274; DUF4070.
DR   InterPro; IPR006638; Elp3/MiaB/NifB.
DR   InterPro; IPR034530; HpnP-like.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR023404; rSAM_horseshoe.
DR   Pfam; PF02310; B12-binding; 1.
DR   Pfam; PF13282; DUF4070; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDF00303; hopanoid_C2-methyltransferase; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SMART; SM00729; Elp3; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   4: Predicted;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Methyltransferase;
KW   Reference proteome; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..536
FT                   /note="Uncharacterized methyltransferase sll1242"
FT                   /id="PRO_0000157884"
FT   DOMAIN          163..394
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         177
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
FT   BINDING         181
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
FT   BINDING         184
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   536 AA;  61756 MW;  715F06F2C2D684E3 CRC64;
     MRALLIYPLF PPTFWSYEKI LELVGRKVLL PPLGLITVAG ILPQEWEFKL VDRNVRNVTE
     AEWDWAEVVI ISGMIVQRDD MVENIKEAKA HGKLVAVGGP FATSVPDEVQ NAGADFLILD
     EGEITLPLFV EALERGETAG IIRAQEKPDV TTTPIPRYDL LELDAYDSMS VQFSRGCPFQ
     CEFCDIIVLY GRKPRTKEPA QLLRELDYLY ELGWRRSVFM VDDNFIGNKR NVKLLLKELK
     VWQEEHQYPF RFNTEASVDL ADDQELMDLM VECYFDAVFL GIETPDEESL EFTKKFQNTR
     NSLADSVDKI IKAGLRPMAG FIIGFDGEKQ GAGDRIVRFA EQTAIPTTTF AMLQALPNTA
     LWHRLKRENR LLDESKGNIN QTTLMNFIPT RPLEDIANEY VEAFWELYDP HGYLDRNYRC
     FLKLGAPKCK TAFKLPNLVD LKALAIVIWR QGVKRDTRFR FWHHAFGILR HNPAVFEHYI
     TLCAHNEHFL QYREIVRQEI GEQLRDYLSR QQQDKVEETV LSPTAIAAET EKVLAS