ID   CAPSD_BNYVS             Reviewed;         690 AA.
AC   O11840;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 2.
DT   29-SEP-2021, entry version 55.
DE   RecName: Full=Capsid readthrough protein;
DE   AltName: Full=CP-RT;
GN   ORFNames=ORF2-ORF3;
OS   Beet necrotic yellow vein virus (isolate Japan/S) (BNYVV).
OC   Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes;
OC   Hepelivirales; Benyviridae; Benyvirus.
OX   NCBI_TaxID=652670;
OH   NCBI_TaxID=343494; Beta macrocarpa (Beet) (Beta vulgaris subsp. macrocarpa).
OH   NCBI_TaxID=161934; Beta vulgaris (Sugar beet).
OH   NCBI_TaxID=3562; Spinacia oleracea (Spinach).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC RNA] (ISOFORM CAPSID PROTEIN AND CAPSID
RP   READTHROUGH PROTEIN).
RX   PubMed=8973531; DOI=10.1007/bf01718223;
RA   Saito M., Kiguchi T., Kusume T., Tamada T.;
RT   "Complete nucleotide sequence of the Japanese isolate S of beet necrotic
RT   yellow vein virus RNA and comparison with European isolates.";
RL   Arch. Virol. 141:2163-2175(1996).
RN   [2]
RP   FUNCTION, AND SUBCELLULAR LOCATION.
RX   PubMed=8279955; DOI=10.1007/bf01379118;
RA   Haeberle A.M., Stussi-Garaud C., Schmitt C., Garaud J.C., Richards K.E.,
RA   Guilley H., Jonard G.;
RT   "Detection by immunogold labelling of P75 readthrough protein near an
RT   extremity of beet necrotic yello w vein virus particles.";
RL   Arch. Virol. 134:195-203(1994).
RN   [3]
RP   MUTAGENESIS OF 553-LYS--GLU-555.
RX   PubMed=8757975; DOI=10.1099/0022-1317-77-7-1359;
RA   Tamada T., Schmitt C., Saito M., Guilley H., Richards K., Jonard G.;
RT   "High resolution analysis of the readthrough domain of beet necrotic yellow
RT   vein virus readthrough protein: a KTER motif is important for efficient
RT   transmission of the virus by Polymyxa betae.";
RL   J. Gen. Virol. 77:1359-1367(1996).
CC   -!- FUNCTION: [Isoform Capsid protein]: Self-assembles to form a helical
CC       capsid wrapping up the viral genomic DNA. {ECO:0000269|PubMed:8279955}.
CC   -!- FUNCTION: [Isoform Capsid readthrough protein]: Minor capsid protein
CC       involved in virus transmission by the vector S.subterranea.
CC       {ECO:0000269|PubMed:8279955}.
CC   -!- SUBCELLULAR LOCATION: [Capsid readthrough protein]: Virion
CC       {ECO:0000269|PubMed:8279955}. Note=Associated with one extremity of
CC       viral particles. {ECO:0000269|PubMed:8279955}.
CC   -!- SUBCELLULAR LOCATION: [Isoform Capsid protein]: Virion
CC       {ECO:0000269|PubMed:8279955}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Ribosomal frameshifting; Named isoforms=2;
CC       Name=Capsid readthrough protein; Synonyms=CP-RT;
CC         IsoId=O11840-1; Sequence=Displayed;
CC       Name=Capsid protein; Synonyms=CP;
CC         IsoId=O11840-2; Sequence=VSP_047620;
CC   -!- MISCELLANEOUS: This protein is translated as a fusion protein by
CC       episodic readthrough of the termination codon at the end of the capsid
CC       protein. Readthrough of the terminator codon TAG occurs between the
CC       codons for Gln-188 and Gln-190 in about 10% of translation events,
CC       thereby producing the 75 kDa readthrough protein (PubMed:8757975).
CC       {ECO:0000305|PubMed:8757975}.
CC   -!- SIMILARITY: Belongs to the virgaviridae capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; D84411; BAA18968.2; -; Genomic_RNA.
DR   RefSeq; NP_612616.2; NC_003515.1.
DR   PRIDE; O11840; -.
DR   GeneID; 991083; -.
DR   KEGG; vg:991083; -.
DR   Proteomes; UP000001100; Genome.
DR   GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   Gene3D; 1.20.120.70; -; 1.
DR   InterPro; IPR001337; TMV-like_coat.
DR   InterPro; IPR036417; TMV-like_coat_sf.
DR   Pfam; PF00721; TMV_coat; 1.
PE   1: Evidence at protein level;
KW   Capsid protein; Coiled coil; Helical capsid protein; Reference proteome;
KW   Ribosomal frameshifting; Virion.
FT   CHAIN           1..690
FT                   /note="Capsid readthrough protein"
FT                   /id="PRO_5000140115"
FT   REGION          583..628
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          451..509
FT                   /evidence="ECO:0000255"
FT   MOTIF           553..556
FT                   /note="Involved in virus transmission by the vector"
FT   VAR_SEQ         189..690
FT                   /note="Missing (in isoform Capsid protein)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_047620"
FT   MUTAGEN         553..555
FT                   /note="KTE->ATA: Complete loss of virus transmission by the
FT                   vector."
FT                   /evidence="ECO:0000269|PubMed:8757975"
SQ   SEQUENCE   690 AA;  74700 MW;  9625389D554AF727 CRC64;
     MSSEGRYMTW KDMSHNKFMT DRWARVSDVV SVIKQSHAMD LSKAANLSII KTALAGLGSG
     WTDNNPFVSP MTRFPQTLTM YGALVLYVNL SDPEFALIMT KVSTLTDSGL ADNASANVRR
     DVVSGNKAES SGKTAGTNEN SAYTLTVSLA GLAQALRLEE LMWTRDKFED RLKLPWTPVQ
     GRTSPPGQXQ LAAARVTAHI RAAKRALLYP GDSPEWVGWK HFYPPPPYDV YDVPPLDIIN
     AKLAADDIGG LVTPTPASSH GLPFEVSEEV EQANRNSLWL TVGLLLAALA VGIGVAAYHR
     KKLQSRLREL KLLWGSTGGS GGGGGFDTEL YMRATDTVSL GTTLSEHAAS APSGLRHRPA
     ATDSGPHEAL PFEVWVFDNL AVVYDSIGMS DLFYTVREFV GVFNGEFEGL IELLESPDDD
     DGVYTNAPRD TAIDAYESQE NYDRIDIETV LIERRINLKK LLLEEAELER RERDMTMIAD
     EEQRTLLHRL ESSRVEATHA VAKAEADARA AVAMAALASK EANDYDSKMA FDRSCKEQEL
     RLRELEVNSM PSKTERYVHT GIQGGAQLAG AMAVGAMLRR GAGSSSQTVS SGANIGSRSQ
     SLTRGRSASQ PLSSVGGSTR GVNNNISNTN LVRAGNSAEV SAGRSTNSGN SNFWSKLRVG
     EGWSKYSVER AATRAQRAIV LPAPPSAPAG