ID   Y1247_HELPY             Reviewed;         340 AA.
AC   O25842;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Protein HP_1247;
GN   OrderedLocusNames=HP_1247;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
RN   [2]
RP   INTERACTION.
RA   Legrain P.;
RL   Unpublished observations (APR-2000).
CC   -!- FUNCTION: Could be the functional equivalent of DNA polymerase III
CC       delta subunit (HolA).
CC   -!- SUBUNIT: Seems to interact with H.pylori HolB.
CC   -!- INTERACTION:
CC       O25842; O25829: HP_1231; NbExp=3; IntAct=EBI-527915, EBI-527926;
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DR   EMBL; AE000511; AAD08299.1; -; Genomic_DNA.
DR   PIR; G64675; G64675.
DR   RefSeq; NP_208039.1; NC_000915.1.
DR   RefSeq; WP_000285823.1; NC_018939.1.
DR   AlphaFoldDB; O25842; -.
DR   SMR; O25842; -.
DR   DIP; DIP-3679N; -.
DR   IntAct; O25842; 1.
DR   MINT; O25842; -.
DR   STRING; 85962.C694_06445; -.
DR   PaxDb; O25842; -.
DR   DNASU; 898813; -.
DR   EnsemblBacteria; AAD08299; AAD08299; HP_1247.
DR   KEGG; hpy:HP_1247; -.
DR   PATRIC; fig|85962.47.peg.1339; -.
DR   eggNOG; COG1466; Bacteria.
DR   OMA; DFFIHYY; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0009360; C:DNA polymerase III complex; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006261; P:DNA-templated DNA replication; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR010372; DNA_pol3_delta_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF06144; DNA_pol3_delta; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   1: Evidence at protein level;
KW   DNA replication; DNA-directed DNA polymerase; Nucleotidyltransferase;
KW   Reference proteome; Transferase.
FT   CHAIN           1..340
FT                   /note="Protein HP_1247"
FT                   /id="PRO_0000105507"
SQ   SEQUENCE   340 AA;  39490 MW;  3BD4151FD5961964 CRC64;
     MYRKDLDHYL KQRLPKAVFL YGEFDFFIHY YIQTISALFK CDNPDIETSL FYASDYEKSQ
     IATLLEQDSL FGGSSLVVLK LDFALHKKFK ENDINLFLKA LERPSHNRLI IGLYNAKSDT
     TKYKYTSDAI VKFFQKSPLK DEAICARFFI PKTWESLKFL QERANFLHLD ISGHLLNALF
     EINNEDLGVS FNDLDKLAVL NAPITLEDIQ ELSSNAGDMD LQKLILGLFL KKSALDIYDY
     LLKEGKKDAD ILRGLERYFY QLFLFFAHIK TTGLMDAKEV LGYAPPKEIA ENYAKNALRL
     KEAGYKRVFE IFRLWHIQSM QGQKELGFLY LTSIQKIINP