ID   Y124_THEMA              Reviewed;         240 AA.
AC   Q9WXX8;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Probable metal transport system ATP-binding protein TM_0124;
GN   OrderedLocusNames=TM_0124;
OS   Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS   / MSB8).
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX   NCBI_TaxID=243274;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8;
RX   PubMed=10360571; DOI=10.1038/20601;
RA   Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA   Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A.,
RA   Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA   Cotton M.D., Pratt M.S., Phillips C.A., Richardson D.L., Heidelberg J.F.,
RA   Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L.,
RA   Smith H.O., Venter J.C., Fraser C.M.;
RT   "Evidence for lateral gene transfer between Archaea and Bacteria from
RT   genome sequence of Thermotoga maritima.";
RL   Nature 399:323-329(1999).
CC   -!- FUNCTION: Part of an ATP-driven transport system
CC       TM_0123/TM_0124/TM_0125 for a metal. Probably responsible for energy
CC       coupling to the transport system.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
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DR   EMBL; AE000512; AAD35218.1; -; Genomic_DNA.
DR   PIR; D72415; D72415.
DR   RefSeq; NP_227940.1; NC_000853.1.
DR   RefSeq; WP_004082707.1; NZ_CP011107.1.
DR   AlphaFoldDB; Q9WXX8; -.
DR   SMR; Q9WXX8; -.
DR   STRING; 243274.THEMA_04185; -.
DR   DNASU; 896951; -.
DR   EnsemblBacteria; AAD35218; AAD35218; TM_0124.
DR   KEGG; tma:TM0124; -.
DR   eggNOG; COG1121; Bacteria.
DR   InParanoid; Q9WXX8; -.
DR   OMA; GHDHVHP; -.
DR   OrthoDB; 1721927at2; -.
DR   Proteomes; UP000008183; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome; Transport.
FT   CHAIN           1..240
FT                   /note="Probable metal transport system ATP-binding protein
FT                   TM_0124"
FT                   /id="PRO_0000093278"
FT   DOMAIN          4..223
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         36..43
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   240 AA;  27586 MW;  134E023F78AF7B91 CRC64;
     MKIVEVKNLT YRINDFEILK NVTFSVEEGE FVGIIGPNGA GKTTLVRILV GDIKNYEGKV
     EVRGKIGYLP QLHQVQREFP ITVKEFAAMG MYGRYRKIDW EKVRSTLKDV GILHKENDPI
     KNLSGGEFQR LSLARALLSD PDILVLDEPE AGVDEMGKAS FYELLNRLRK EKNITVIMVS
     HDIGMVFKEC STIMCLNRTL HCHGPTETIN PEDLKKIFTD FDIWIRGTRH YEIYHGRERD