ID   Y1251_HAEIN             Reviewed;         107 AA.
AC   Q57089; O05048;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator HI_1251;
GN   OrderedLocusNames=HI_1251;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SIMILARITY: Belongs to the VapA/VapI family. {ECO:0000305}.
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DR   EMBL; L42023; AAC22901.1; -; Genomic_DNA.
DR   PIR; H64112; H64112.
DR   RefSeq; NP_439407.1; NC_000907.1.
DR   RefSeq; WP_005650217.1; NC_000907.1.
DR   AlphaFoldDB; Q57089; -.
DR   SMR; Q57089; -.
DR   STRING; 71421.HI_1251; -.
DR   EnsemblBacteria; AAC22901; AAC22901; HI_1251.
DR   KEGG; hin:HI_1251; -.
DR   PATRIC; fig|71421.8.peg.1303; -.
DR   eggNOG; COG3093; Bacteria.
DR   HOGENOM; CLU_140230_3_2_6; -.
DR   OMA; GNSAKFW; -.
DR   PhylomeDB; Q57089; -.
DR   BioCyc; HINF71421:G1GJ1-1282-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR013430; Toxin_antidote_HigA.
DR   PANTHER; PTHR36924; PTHR36924; 1.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   TIGRFAMs; TIGR02607; antidote_HigA; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..107
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   HI_1251"
FT                   /id="PRO_0000149755"
FT   DOMAIN          13..68
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        24..43
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
SQ   SEQUENCE   107 AA;  12347 MW;  3BBCD65C7F14B798 CRC64;
     MMTRKPTSVG EILQEEFLEP LSLKISDLAQ ILDVHRNTAS NIVNNSSRIT LEMAVKLAKV
     FDTTPEFWLN LQTRIDLWDL EHNKRFQQSL ANVKPALHRH DTSTFAM