ID   Y1252_RICFE             Reviewed;         301 AA.
AC   Q4UK32;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 2.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Uncharacterized membrane protein RF_1252;
GN   OrderedLocusNames=RF_1252;
OS   Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) (Rickettsia azadi).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=315456;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-1525 / URRWXCal2;
RX   PubMed=15984913; DOI=10.1371/journal.pbio.0030248;
RA   Ogata H., Renesto P., Audic S., Robert C., Blanc G., Fournier P.-E.,
RA   Parinello H., Claverie J.-M., Raoult D.;
RT   "The genome sequence of Rickettsia felis identifies the first putative
RT   conjugative plasmid in an obligate intracellular parasite.";
RL   PLoS Biol. 3:1-12(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the TerC family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAY62103.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; CP000053; AAY62103.1; ALT_FRAME; Genomic_DNA.
DR   AlphaFoldDB; Q4UK32; -.
DR   STRING; 315456.RF_1252; -.
DR   EnsemblBacteria; AAY62103; AAY62103; RF_1252.
DR   KEGG; rfe:RF_1252; -.
DR   eggNOG; COG0861; Bacteria.
DR   HOGENOM; CLU_045644_1_2_5; -.
DR   Proteomes; UP000008548; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005496; Integral_membrane_TerC.
DR   InterPro; IPR022369; Integral_membrane_TerC_rswitch.
DR   PANTHER; PTHR30238:SF0; PTHR30238:SF0; 1.
DR   Pfam; PF03741; TerC; 1.
DR   TIGRFAMs; TIGR03718; R_switched_Alx; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..301
FT                   /note="Uncharacterized membrane protein RF_1252"
FT                   /id="PRO_0000294412"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        246..266
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        270..290
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   301 AA;  34739 MW;  14AAFB8C13A89762 CRC64;
     MSWIIFYTVI AALLVLDLGI VHKKNTVMSF KESVLFSLFY FVIACLFGIY FYYNTGAEHA
     REYYTCFLIE KAMSLDNIFV ISIIFQFFKI PGKYQHRVLF FGIIGVIIFR AIMIYGGTIL
     INKFAWLLYI FAVILIATGI KTFYVSHKTF DIQNSYIYKS IVKNLNITPN LEGDKFVVKR
     NNKLYFTPLF ISLVLIEAID LVFAIDSIPA IFAITNDVYI IYTSNIFAIL GLRALFFCLA
     EIVERFSYIK YSLALILIFI GFKIFIHHYI AIPAYVSLIV TITLLLFGII ASIIRKNMID
     H