ID   Y1253_HAEIN             Reviewed;         127 AA.
AC   P44139;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Protein HI_1253;
GN   OrderedLocusNames=HI_1253;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000250|UniProtKB:Q46755}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the SirB2 family. {ECO:0000305}.
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DR   EMBL; L42023; AAC22903.1; -; Genomic_DNA.
DR   PIR; D64023; D64023.
DR   RefSeq; NP_439409.1; NC_000907.1.
DR   AlphaFoldDB; P44139; -.
DR   STRING; 71421.HI_1253; -.
DR   EnsemblBacteria; AAC22903; AAC22903; HI_1253.
DR   KEGG; hin:HI_1253; -.
DR   PATRIC; fig|71421.8.peg.1305; -.
DR   eggNOG; COG3094; Bacteria.
DR   HOGENOM; CLU_123860_4_0_6; -.
DR   OMA; MVDWRQY; -.
DR   PhylomeDB; P44139; -.
DR   BioCyc; HINF71421:G1GJ1-1284-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   InterPro; IPR007360; SirB.
DR   PANTHER; PTHR39594; PTHR39594; 1.
DR   Pfam; PF04247; SirB; 1.
DR   PIRSF; PIRSF005610; SirB; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..127
FT                   /note="Protein HI_1253"
FT                   /id="PRO_0000078015"
FT   TRANSMEM        13..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   127 AA;  14576 MW;  023B5AA8DF9C6D8D CRC64;
     MNFDRTFLTF LGVIMLVHLH IFFAFLSLAL LVIRGAMQLN GKNWRSIKLL KILPHLSDTL
     LIVSGVVILY LFAFGIEWWL VAKFALLILY IVFAAKFFSK KVSQPKSIFF WLACVSFIGA
     MLIAYLK