Y1254_IGNH4
ID Y1254_IGNH4 Reviewed; 233 AA.
AC A8ABX8;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 64.
DE RecName: Full=UPF0173 metal-dependent hydrolase Igni_1254 {ECO:0000255|HAMAP-Rule:MF_00457};
GN OrderedLocusNames=Igni_1254;
OS Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125).
OC Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC Desulfurococcaceae; Ignicoccus.
OX NCBI_TaxID=453591;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KIN4/I / DSM 18386 / JCM 14125;
RX PubMed=19000309; DOI=10.1186/gb-2008-9-11-r158;
RA Podar M., Anderson I., Makarova K.S., Elkins J.G., Ivanova N., Wall M.A.,
RA Lykidis A., Mavromatis K., Sun H., Hudson M.E., Chen W., Deciu C.,
RA Hutchison D., Eads J.R., Anderson A., Fernandes F., Szeto E., Lapidus A.,
RA Kyrpides N.C., Saier M.H. Jr., Richardson P.M., Rachel R., Huber H.,
RA Eisen J.A., Koonin E.V., Keller M., Stetter K.O.;
RT "A genomic analysis of the archaeal system Ignicoccus hospitalis-
RT Nanoarchaeum equitans.";
RL Genome Biol. 9:R158.1-R158.18(2008).
CC -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC Rule:MF_00457}.
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DR EMBL; CP000816; ABU82430.1; -; Genomic_DNA.
DR RefSeq; WP_012123394.1; NC_009776.1.
DR PDB; 6HRG; X-ray; 2.12 A; A=1-233.
DR PDBsum; 6HRG; -.
DR AlphaFoldDB; A8ABX8; -.
DR SMR; A8ABX8; -.
DR STRING; 453591.Igni_1254; -.
DR EnsemblBacteria; ABU82430; ABU82430; Igni_1254.
DR GeneID; 5562727; -.
DR KEGG; iho:Igni_1254; -.
DR eggNOG; arCOG00497; Archaea.
DR HOGENOM; CLU_070010_4_0_2; -.
DR OMA; WHGHSTW; -.
DR OrthoDB; 76909at2157; -.
DR PhylomeDB; A8ABX8; -.
DR Proteomes; UP000000262; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.60.15.10; -; 1.
DR HAMAP; MF_00457; UPF0173; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR022877; UPF0173.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; SSF56281; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Hydrolase; Reference proteome.
FT CHAIN 1..233
FT /note="UPF0173 metal-dependent hydrolase Igni_1254"
FT /id="PRO_0000367228"
FT STRAND 3..8
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 14..20
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 22..26
FT /evidence="ECO:0007829|PDB:6HRG"
FT HELIX 38..44
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 48..51
FT /evidence="ECO:0007829|PDB:6HRG"
FT HELIX 57..60
FT /evidence="ECO:0007829|PDB:6HRG"
FT HELIX 63..70
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 73..77
FT /evidence="ECO:0007829|PDB:6HRG"
FT HELIX 78..86
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 91..94
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 96..98
FT /evidence="ECO:0007829|PDB:6HRG"
FT TURN 103..105
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 109..114
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 128..133
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 136..141
FT /evidence="ECO:0007829|PDB:6HRG"
FT HELIX 151..158
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 161..166
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 170..172
FT /evidence="ECO:0007829|PDB:6HRG"
FT HELIX 175..185
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 188..194
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 196..198
FT /evidence="ECO:0007829|PDB:6HRG"
FT HELIX 199..201
FT /evidence="ECO:0007829|PDB:6HRG"
FT HELIX 205..214
FT /evidence="ECO:0007829|PDB:6HRG"
FT STRAND 228..232
FT /evidence="ECO:0007829|PDB:6HRG"
SQ SEQUENCE 233 AA; 25437 MW; A133E8FE53721C58 CRC64;
MTTVKLTYFG HSAFHVEVDG VGIAIDPWIT NPLSKTTLED YLKNFKTDLV VITHAHEDHI
GDALEIMRRT GAKFFSIHEI YVDLTQKGFQ GIGANIGGPA KLDDVAPGLG IALTPATHSS
YDKGVPTGAI IFKDGKALVY HAGDTGLFAE MQFIGELYAP KVALLPIGGH YTMDIEQALL
ATKLLRPEVV VPMHYNTFPP IRADPNEFKQ KVESAGLAKV RVMEPGETVT FEF
