ID   Y1254_METJA             Reviewed;         469 AA.
AC   Q58651;
DT   06-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 104.
DE   RecName: Full=Uncharacterized protein MJ1254;
GN   OrderedLocusNames=MJ1254;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; L77117; AAB99266.1; -; Genomic_DNA.
DR   PIR; E64456; E64456.
DR   RefSeq; WP_010870767.1; NC_000909.1.
DR   AlphaFoldDB; Q58651; -.
DR   SMR; Q58651; -.
DR   STRING; 243232.MJ_1254; -.
DR   DNASU; 1452152; -.
DR   EnsemblBacteria; AAB99266; AAB99266; MJ_1254.
DR   GeneID; 1452152; -.
DR   KEGG; mja:MJ_1254; -.
DR   eggNOG; arCOG00391; Archaea.
DR   HOGENOM; CLU_637154_0_0_2; -.
DR   OMA; QVYIIVP; -.
DR   OrthoDB; 52593at2157; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   SUPFAM; SSF46785; SSF46785; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..469
FT                   /note="Uncharacterized protein MJ1254"
FT                   /id="PRO_0000107242"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   469 AA;  53926 MW;  E4FBDDCA1C1E3453 CRC64;
     MIAFLFYKCF AKNYKINFLY KNSSYINTNT LWLKVIYIKT KDVIIFLLLF FVAFNVSSAY
     VIKNLNIDCI VTPDDTINET ISFVIYNNED KNLSHISYTI PQTIRNFTIN ASAGVKGYSA
     LYNEGVTEIA IEFEKPIPKG GYTNITINCF VNDAIWTKNG IKQLILSFPI TSKNATIKIV
     LPPGAVILSP QGTLLVTPSG YKITTDGKHQ IIVWDLSLNK EITFTITVKY TFISYPGQNI
     IEQPAINNNL KYLLIIAIFG TAIFGGLFVK EKISKRKIIE RTKNIKNELT SLKNKLKEKE
     EEIKNLAIKI KDLEDKLSKA NKNLLNKDEI ISVLNERISE YESQIQKLLD ENIIYKEKIE
     SLNKYIETLK KENDKLKDKV RELSDIAKKY MEEKRGVLWS FLTEDEKIII DLIKKHGHIT
     QKEIVEITGM SKPKVSRIIS ELEDRKIIRK EKIGRINKLT LTEESKKLL