ID   Y1255_MYCTO             Reviewed;         202 AA.
AC   P9WMD4; L0T641; Q11063;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator MT1294;
GN   OrderedLocusNames=MT1294;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
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DR   EMBL; AE000516; AAK45552.1; -; Genomic_DNA.
DR   PIR; G70752; G70752.
DR   RefSeq; WP_003406350.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WMD4; -.
DR   SMR; P9WMD4; -.
DR   EnsemblBacteria; AAK45552; AAK45552; MT1294.
DR   GeneID; 45425225; -.
DR   KEGG; mtc:MT1294; -.
DR   PATRIC; fig|83331.31.peg.1397; -.
DR   HOGENOM; CLU_069356_39_4_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   Pfam; PF00440; TetR_N; 1.
DR   PRINTS; PR00455; HTHTETR.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding; Repeat; Transcription; Transcription regulation.
FT   CHAIN           1..202
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   MT1294"
FT                   /id="PRO_0000427323"
FT   DOMAIN          13..73
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT   DNA_BIND        36..55
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   202 AA;  22223 MW;  78934C8E146DC0BB CRC64;
     MAGTDWLSAR RTELAADRIL DAAERLFTQR DPASIGMNEI AKAAGCSRAT LYRYFDSREA
     LRTAYVHRET RRLGREIMVK IADVVEPAER LLVSITTTLR MVRDNPALAA WFTTTRPPIG
     GEMAGRSEVI AALAAAFLNS LGPDDPTTVE RRARWVVRML TSLLMFPGRD EADERAMIAE
     FVVPIVTPAS AAARKAGHPG PE