ID   Y1257_METJA             Reviewed;         349 AA.
AC   Q58654;
DT   24-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Uncharacterized protein MJ1257;
GN   OrderedLocusNames=MJ1257;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
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DR   EMBL; L77117; AAB99268.1; -; Genomic_DNA.
DR   PIR; H64456; H64456.
DR   RefSeq; WP_010870770.1; NC_000909.1.
DR   AlphaFoldDB; Q58654; -.
DR   SMR; Q58654; -.
DR   STRING; 243232.MJ_1257; -.
DR   PRIDE; Q58654; -.
DR   EnsemblBacteria; AAB99268; AAB99268; MJ_1257.
DR   GeneID; 1452155; -.
DR   KEGG; mja:MJ_1257; -.
DR   eggNOG; arCOG00056; Archaea.
DR   HOGENOM; CLU_775255_0_0_2; -.
DR   InParanoid; Q58654; -.
DR   OMA; NCVVDIG; -.
DR   OrthoDB; 40605at2157; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0032259; P:methylation; IEA:InterPro.
DR   GO; GO:0052837; P:thiazole biosynthetic process; IBA:GO_Central.
DR   GO; GO:0002937; P:tRNA 4-thiouridine biosynthesis; IBA:GO_Central.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR004114; THUMP_dom.
DR   Pfam; PF01728; FtsJ; 1.
DR   Pfam; PF02926; THUMP; 1.
DR   SMART; SM00981; THUMP; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   PROSITE; PS51165; THUMP; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..349
FT                   /note="Uncharacterized protein MJ1257"
FT                   /id="PRO_0000107243"
FT   DOMAIN          51..160
FT                   /note="THUMP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00529"
SQ   SEQUENCE   349 AA;  41198 MW;  D0A061A05D8CA5C7 CRC64;
     MKPVALVTTK PGFEPQLREE LNKLPIKKKI LWTPFRGILK VLSQNPYEFL NIIKENKNNL
     KFSLRIIPLE IGCQTDINEI KKAISFLINK KKEKLKNKSF VVRCNRRGNH EFTSEELERI
     IGEYVLENFK DLNLRVNLKD WDFKINIEIL QDESYISIFQ DEFNELVIEE NIKNLKNLKR
     YIERPLNRSE RKMQELMEKF PFIFENINCV VDIGSSPGGW AKMLSKKAKK VYAIDTGELK
     IKANNIIHIK KRAENVDFEK DINEEIDLIT NDTNLYPDES LFLTLKFAKH LKTNGYIIHT
     LKARNLKTKK EDLEKVLKIL SYYRNIKIFK IINLRANTKN ELTLILKKV