Y125_THEMA
ID Y125_THEMA Reviewed; 282 AA.
AC Q9WXX9;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 25-MAY-2022, entry version 109.
DE RecName: Full=Probable metal transport system membrane protein TM_0125;
GN OrderedLocusNames=TM_0125;
OS Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826
OS / MSB8).
OC Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX NCBI_TaxID=243274;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8;
RX PubMed=10360571; DOI=10.1038/20601;
RA Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H.,
RA Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A.,
RA Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M.,
RA Cotton M.D., Pratt M.S., Phillips C.A., Richardson D.L., Heidelberg J.F.,
RA Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L.,
RA Smith H.O., Venter J.C., Fraser C.M.;
RT "Evidence for lateral gene transfer between Archaea and Bacteria from
RT genome sequence of Thermotoga maritima.";
RL Nature 399:323-329(1999).
CC -!- FUNCTION: Part of an ATP-driven transport system
CC TM_0123/TM_0124/TM_0125 for a metal.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ABC-3 integral membrane protein family.
CC {ECO:0000305}.
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DR EMBL; AE000512; AAD35219.1; -; Genomic_DNA.
DR PIR; E72415; E72415.
DR RefSeq; NP_227941.1; NC_000853.1.
DR AlphaFoldDB; Q9WXX9; -.
DR SMR; Q9WXX9; -.
DR STRING; 243274.THEMA_04180; -.
DR EnsemblBacteria; AAD35219; AAD35219; TM_0125.
DR KEGG; tma:TM0125; -.
DR PATRIC; fig|243274.5.peg.123; -.
DR eggNOG; COG1108; Bacteria.
DR InParanoid; Q9WXX9; -.
DR OMA; RIDLMAY; -.
DR Proteomes; UP000008183; Chromosome.
DR GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IEA:InterPro.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0010043; P:response to zinc ion; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.3470.10; -; 1.
DR InterPro; IPR037294; ABC_BtuC-like.
DR InterPro; IPR001626; ABC_TroCD.
DR PANTHER; PTHR30477; PTHR30477; 1.
DR Pfam; PF00950; ABC-3; 1.
DR SUPFAM; SSF81345; SSF81345; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..282
FT /note="Probable metal transport system membrane protein
FT TM_0125"
FT /id="PRO_0000171174"
FT TRANSMEM 33..53
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 58..78
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 109..129
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 184..204
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 210..230
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 234..254
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 259..279
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 282 AA; 30769 MW; 90915278A9749E99 CRC64;
MDQRNKTLRD LPWEGERLSF FHDLVEYSFL RTAFVGGILV ASLSGLVSPI VVFRRMEFIG
DGTAHAVFAG LAAATLIGAD HRLIAFATAL LFAFAVSLFS RSRISESSAI GILLPFFMAV
GVVLFSVSGR YQTDVMGYLF GDVLLVNSTD VAITAVVLAL SVILTVVFRW DIKYFIVDEK
MARFYGIKTD LIRFLITSFI AITVVTTVKV VGVILTGALL ILPGLVSKIF GKSFWSLTTI
SVIFSTGVFF AGFLTAYTLD LPPGPVIVII AFVSFLPMLK FS
