CAPSD_BPF1
ID CAPSD_BPF1 Reviewed; 73 AA.
AC P69540; P03617;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=Capsid protein G8P;
DE AltName: Full=Coat protein B;
DE AltName: Full=Gene 8 protein;
DE Short=G8P;
DE AltName: Full=Major coat protein;
DE Flags: Precursor;
GN Name=VIII;
OS Enterobacteria phage f1 (Bacteriophage f1).
OC Viruses; Monodnaviria; Loebvirae; Hofneiviricota; Faserviricetes;
OC Tubulavirales; Inoviridae; Inovirus.
OX NCBI_TaxID=10863;
OH NCBI_TaxID=562; Escherichia coli.
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=6282703; DOI=10.1016/0378-1119(81)90059-7;
RA Beck E., Zink B.;
RT "Nucleotide sequence and genome organisation of filamentous bacteriophages
RT f1 and fd.";
RL Gene 16:35-58(1981).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=7373712; DOI=10.1128/jvi.34.1.40-50.1980;
RA Hill D.F., Petersen G.B.;
RT "Nucleotide sequences in bacteriophage f1 DNA: nucleotide sequence of genes
RT V, VII, and VIII.";
RL J. Virol. 34:40-50(1980).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=6292494; DOI=10.1128/jvi.44.1.32-46.1982;
RA Hill D.F., Petersen G.B.;
RT "Nucleotide sequence of bacteriophage f1 DNA.";
RL J. Virol. 44:32-46(1982).
RN [4]
RP PROTEIN SEQUENCE OF 24-73.
RX PubMed=321454; DOI=10.1016/s0021-9258(17)40544-8;
RA Bailey G.S., Gillett D., Hill D.F., Petersen G.B.;
RT "Automated sequencing of insoluble peptides using detergent. Bacteriophage
RT f1 coat protein.";
RL J. Biol. Chem. 252:2218-2225(1977).
CC -!- FUNCTION: Self assembles to form a helical capsid wrapping up the viral
CC genomic DNA. The capsid displays a filamentous structure with a length
CC of 760-1950 nm and a width of 6-8 nm. The virion assembly and budding
CC take place at the host inner membrane (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Homomultimerizes. There are several thousands of this protein
CC in the phage capsid (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000305}. Host membrane; Single-pass
CC type I membrane protein. Note=prior to assembly, the major capsid
CC protein is found associated with the bacterial host inner membrane.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the inovirus capsid protein family.
CC {ECO:0000305}.
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DR EMBL; V00606; CAA23871.1; -; Genomic_DNA.
DR EMBL; J02450; AAA32220.1; -; Genomic_DNA.
DR EMBL; J02448; AAA32214.1; -; Genomic_DNA.
DR PIR; E04226; VCBPF1.
DR BMRB; P69540; -.
DR SMR; P69540; -.
DR Proteomes; UP000002557; Genome.
DR Proteomes; UP000241027; Genome.
DR GO; GO:0019029; C:helical viral capsid; IEA:UniProtKB-KW.
DR GO; GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.80; -; 1.
DR InterPro; IPR008020; G8P.
DR InterPro; IPR023390; Phage_M13_G8P_capsid_dom_sf.
DR Pfam; PF19199; Phage_coatGP8; 1.
DR PIRSF; PIRSF004117; Phage_coat_B; 1.
PE 1: Evidence at protein level;
KW Capsid protein; Direct protein sequencing; Helical capsid protein;
KW Host membrane; Membrane; Signal; Transmembrane; Transmembrane helix;
KW Virion.
FT SIGNAL 1..23
FT /evidence="ECO:0000269|PubMed:321454"
FT CHAIN 24..73
FT /note="Capsid protein G8P"
FT /id="PRO_0000003297"
FT TOPO_DOM 24..44
FT /note="Periplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000250"
FT TOPO_DOM 66..73
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
SQ SEQUENCE 73 AA; 7626 MW; 53ACF68DB18E6A52 CRC64;
MKKSLVLKAS VAVATLVPML SFAAEGDDPA KAAFDSLQAS ATEYIGYAWA MVVVIVGATI
GIKLFKKFTS KAS
