ID   Y1265_NOSCE             Reviewed;         244 AA.
AC   C4V9L5;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   03-AUG-2022, entry version 42.
DE   RecName: Full=Putative methyltransferase NCER_101265;
DE            EC=2.1.1.-;
GN   ORFNames=NCER_101265;
OS   Nosema ceranae (strain BRL01) (Microsporidian parasite).
OC   Eukaryota; Fungi; Fungi incertae sedis; Microsporidia; Nosematidae; Nosema.
OX   NCBI_TaxID=578460;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BRL01;
RX   PubMed=19503607; DOI=10.1371/journal.ppat.1000466;
RA   Cornman R.S., Chen Y.P., Schatz M.C., Street C., Zhao Y., Desany B.,
RA   Egholm M., Hutchison S., Pettis J.S., Lipkin W.I., Evans J.D.;
RT   "Genomic analyses of the microsporidian Nosema ceranae, an emergent
RT   pathogen of honey bees.";
RL   PLoS Pathog. 5:E1000466-E1000466(2009).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ACOL01000117; EEQ82091.1; -; Genomic_DNA.
DR   RefSeq; XP_002995762.1; XM_002995716.1.
DR   AlphaFoldDB; C4V9L5; -.
DR   SMR; C4V9L5; -.
DR   STRING; 578460.C4V9L5; -.
DR   PRIDE; C4V9L5; -.
DR   EnsemblFungi; EEQ82091; EEQ82091; NCER_101265.
DR   KEGG; nce:NCER_101265; -.
DR   VEuPathDB; MicrosporidiaDB:NCER_101265; -.
DR   HOGENOM; CLU_029501_2_1_1; -.
DR   InParanoid; C4V9L5; -.
DR   OMA; WEIEALV; -.
DR   Proteomes; UP000009082; Unassembled WGS sequence.
DR   GO; GO:0016300; F:tRNA (uracil) methyltransferase activity; IEA:InterPro.
DR   GO; GO:0002098; P:tRNA wobble uridine modification; IEA:InterPro.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR013216; Methyltransf_11.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR032873; Trm9.
DR   PANTHER; PTHR13069:SF21; PTHR13069:SF21; 1.
DR   Pfam; PF08241; Methyltransf_11; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..244
FT                   /note="Putative methyltransferase NCER_101265"
FT                   /id="PRO_0000388433"
SQ   SEQUENCE   244 AA;  28539 MW;  ECE6433EC0F891E3 CRC64;
     MNSEYEDAYV HKFYSKYAKK FDVTRYKTWP KISSFLKVYD KPGFLNLDAG CGNGRNLPRT
     GGVWIGLDYS KELLNCIVDK YCKVNDQKDL DCGTLSKKNI CKSELKYSLV HKSSSTPHVS
     FNLIRGDCLC LPFNSNTFDI ILSIAVIHHF STPERRTQAL QEMHRVLKPT GRILLYVWNE
     ETKFQSKFKQ IKNKDYLVRF KTFDRYYYLY DHKELVDACV KNGFNVEESG IEQESIFVIL
     KKQI