Y1269_MYCTU
ID Y1269_MYCTU Reviewed; 124 AA.
AC P9WM45; L0T7S6; P0A5E1; Q11050;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 03-AUG-2022, entry version 30.
DE RecName: Full=Protein Rv1269c;
DE Flags: Precursor;
GN OrderedLocusNames=Rv1269c; ORFNames=MTCY50.13;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION BY MASS SPECTROMETRY.
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=11681203;
RX DOI=10.1002/1615-9861(200104)1:4<494::aid-prot494>3.0.co;2-4;
RA Mattow J., Jungblut P.R., Mueller E.-C., Kaufmann S.H.E.;
RT "Identification of acidic, low molecular mass proteins of Mycobacterium
RT tuberculosis strain H37Rv by matrix-assisted laser desorption/ionization
RT and electrospray ionization mass spectrometry.";
RL Proteomics 1:494-507(2001).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- PTM: Predicted to be exported by the Tat system. The position of the
CC signal peptide cleavage has not been experimentally proven.
CC -!- SIMILARITY: To M.tuberculosis Rv1813c. {ECO:0000305}.
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DR EMBL; AL123456; CCP44025.1; -; Genomic_DNA.
DR PIR; E70754; E70754.
DR RefSeq; NP_215785.1; NC_000962.3.
DR RefSeq; WP_003406558.1; NZ_NVQJ01000030.1.
DR AlphaFoldDB; P9WM45; -.
DR SMR; P9WM45; -.
DR STRING; 83332.Rv1269c; -.
DR PaxDb; P9WM45; -.
DR DNASU; 887039; -.
DR GeneID; 45425241; -.
DR GeneID; 887039; -.
DR KEGG; mtu:Rv1269c; -.
DR TubercuList; Rv1269c; -.
DR eggNOG; ENOG502ZK3D; Bacteria.
DR OMA; WGRASHY; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0005576; C:extracellular region; HDA:MTBBASE.
DR GO; GO:0009274; C:peptidoglycan-based cell wall; HDA:MTBBASE.
DR InterPro; IPR025240; DUF4189.
DR InterPro; IPR006311; TAT_signal.
DR Pfam; PF13827; DUF4189; 1.
DR PROSITE; PS51318; TAT; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Signal.
FT SIGNAL 1..35
FT /note="Tat-type signal"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00648"
FT CHAIN 36..124
FT /note="Protein Rv1269c"
FT /id="PRO_0000014089"
SQ SEQUENCE 124 AA; 12550 MW; 1BCECB3EFAE4FC0C CRC64;
MTTMITLRRR FAVAVAGVAT AAATTVTLAP APANAADVYG AIAYSGNGSW GRSWDYPTRA
AAEATAVKSC GYSDCKVLTS FTACGAVAAN DRAYQGGVGP TLAAAMKDAL TKLGGGYIDT
WACN