ID   Y126_TREPA              Reviewed;         291 AA.
AC   O83163;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Uncharacterized protein TP_0126;
GN   OrderedLocusNames=TP_0126;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To T.pallidum TP_0733. {ECO:0000305}.
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DR   EMBL; AE000520; AAC65118.1; -; Genomic_DNA.
DR   PIR; C71362; C71362.
DR   AlphaFoldDB; O83163; -.
DR   IntAct; O83163; 2.
DR   STRING; 243276.TPANIC_0126; -.
DR   TCDB; 1.B.6.10.2; the ompa-ompf porin (oop) family.
DR   EnsemblBacteria; AAC65118; AAC65118; TP_0126.
DR   KEGG; tpa:TP_0126; -.
DR   HOGENOM; CLU_083340_0_0_12; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR011250; OMP/PagP_b-brl.
DR   SUPFAM; SSF56925; SSF56925; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..291
FT                   /note="Uncharacterized protein TP_0126"
FT                   /id="PRO_0000202192"
FT   TRANSMEM        74..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        188..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..55
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   291 AA;  31921 MW;  4963E1BD06EE67A3 CRC64;
     MRTHDIPRSP LVGHKKNAAP DGIGASRACC PARENEPFKK GSTNSRGGGV EWSRSSTRRV
     RGSALERGMK QLKWWAVGPV LGICAGVWGA AHPVHADPWD TTAAGRSTIR LSAMGAVPLF
     QVDWCNSGRG DDRNANAQTN GHKYIYPAFS AALGFEHFVC RGLSLGIDAS VQYHCSYPNN
     TYSPTTPYYY LAIPVALTAG YTVAFWRIRL PLTVGAGFNY QHYYTSTYYG LVLKAAAGCY
     FQLTEHWSLG VSATYSGVPR SCEKIIEEDR QQTNTRTAQF IAAGVDVRYH L