ID   Y1279_MYCTO             Reviewed;         528 AA.
AC   P9WMV4; L0T7T5; P64263; Q11038;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 42.
DE   RecName: Full=Uncharacterized GMC-type oxidoreductase MT1316;
DE            EC=1.1.-.-;
GN   OrderedLocusNames=MT1316;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- COFACTOR:
CC       Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the GMC oxidoreductase family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK45577.1; -; Genomic_DNA.
DR   PIR; G70755; G70755.
DR   RefSeq; WP_003406598.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WMV4; -.
DR   SMR; P9WMV4; -.
DR   EnsemblBacteria; AAK45577; AAK45577; MT1316.
DR   KEGG; mtc:MT1316; -.
DR   PATRIC; fig|83331.31.peg.1422; -.
DR   HOGENOM; CLU_002865_7_2_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR012132; GMC_OxRdtase.
DR   InterPro; IPR000172; GMC_OxRdtase_N.
DR   InterPro; IPR007867; GMC_OxRtase_C.
DR   PANTHER; PTHR11552; PTHR11552; 1.
DR   Pfam; PF05199; GMC_oxred_C; 1.
DR   Pfam; PF00732; GMC_oxred_N; 1.
DR   PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   PROSITE; PS00623; GMC_OXRED_1; 1.
DR   PROSITE; PS00624; GMC_OXRED_2; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase.
FT   CHAIN           1..528
FT                   /note="Uncharacterized GMC-type oxidoreductase MT1316"
FT                   /id="PRO_0000427236"
FT   ACT_SITE        468
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250|UniProtKB:E4QP00"
FT   BINDING         6..35
FT                   /ligand="FAD"
FT                   /ligand_id="ChEBI:CHEBI:57692"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   528 AA;  57331 MW;  9177AD391F994CB6 CRC64;
     MDTQSDYVVV GTGSAGAVVA SRLSTDPATT VVALEAGPRD KNRFIGVPAA FSKLFRSEID
     WDYLTEPQPE LDGREIYWPR GKVLGGSSSM NAMMWVRGFA SDYDEWAARA GPRWSYADVL
     GYFRRIENVT AAWHFVSGDD SGVTGPLHIS RQRSPRSVTA AWLAAARECG FAAARPNSPR
     PEGFCETVVT QRRGARFSTA DAYLKPAMRR KNLRVLTGAT ATRVVIDGDR AVGVEYQSDG
     QTRIVYARRE VVLCAGAVNS PQLLMLSGIG DRDHLAEHDI DTVYHAPEVG CNLLDHLVTV
     LGFDVEKDSL FAAEKPGQLI SYLLRRRGML TSNVGEAYGF VRSRPELKLP DLELIFAPAP
     FYDEALVPPA GHGVVFGPIL VAPQSRGQIT LRSADPHAKP VIEPRYLSDL GGVDRAAMMA
     GLRICARIAQ ARPLRDLLGS IARPRNSTEL DEATLELALA TCSHTLYHPM GTCRMGSDEA
     SVVDPQLRVR GVDGLRVADA SVMPSTVRGH THAPSVLIGE KAADLIRS