ID   CAPSD_BPKPP             Reviewed;         351 AA.
AC   D6RRG1;
DT   14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT   10-AUG-2010, sequence version 1.
DT   02-DEC-2020, entry version 26.
DE   RecName: Full=Major capsid protein {ECO:0000255|HAMAP-Rule:MF_04133};
DE   AltName: Full=Gene product 4 {ECO:0000305};
DE            Short=gp4 {ECO:0000305};
DE   AltName: Full=Major head protein {ECO:0000255|HAMAP-Rule:MF_04133};
GN   ORFNames=ORF4;
OS   Pseudomonas phage KPP10 (Bacteriophage KPP10).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Nankokuvirus.
OX   NCBI_TaxID=582345;
OH   NCBI_TaxID=287; Pseudomonas aeruginosa.
RN   [1] {ECO:0000312|EMBL:BAJ09125.1}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=19457172; DOI=10.1111/j.1348-0421.2009.00125.x;
RA   Uchiyama J., Maeda Y., Takemura I., Chess-Williams R., Wakiguchi H.,
RA   Matsuzaki S.;
RT   "Blood kinetics of four intraperitoneally administered therapeutic
RT   candidate bacteriophages in healthy and neutropenic mice.";
RL   Microbiol. Immunol. 53:301-304(2009).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 1-20, IDENTIFICATION, SUBCELLULAR LOCATION, AND
RP   FUNCTION.
RX   PubMed=22218962; DOI=10.1007/s00705-011-1210-x;
RA   Uchiyama J., Rashel M., Takemura I., Kato S., Ujihara T., Muraoka A.,
RA   Matsuzaki S., Daibata M.;
RT   "Genetic characterization of Pseudomonas aeruginosa bacteriophage KPP10.";
RL   Arch. Virol. 157:733-738(2012).
CC   -!- FUNCTION: Assembles to form an icosahedral capsid. The assembly is
CC       primed by the interaction between capsid assembly protease and portal
CC       dodecamer, and major capsid proteins assemble cooperatively to form the
CC       procapsid with the help of capsid scaffolding protein. Major capsid
CC       protein forms hexons and pentons of the icosahedron. Viral genomic DNA
CC       is packaged into the procapsid through the portal vertex. The packaging
CC       triggers a dramatic reconfiguration of the capsid shell.
CC       {ECO:0000255|HAMAP-Rule:MF_04133}.
CC   -!- SUBUNIT: Homomultimer. {ECO:0000255|HAMAP-Rule:MF_04133}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04133,
CC       ECO:0000269|PubMed:22218962}. Host cytoplasm {ECO:0000255|HAMAP-
CC       Rule:MF_04133}. Note=Forms the capsid icosahedric shell.
CC       {ECO:0000255|HAMAP-Rule:MF_04133}.
CC   -!- SIMILARITY: Belongs to the lambda phage major capsid protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04133}.
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DR   EMBL; AB472900; BAJ09125.1; -; Genomic_DNA.
DR   RefSeq; YP_004306755.1; NC_015272.2.
DR   GeneID; 10358729; -.
DR   KEGG; vg:10358729; -.
DR   Proteomes; UP000000375; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04133; CAPSID_LAMBDA; 1.
DR   InterPro; IPR005564; Major_capsid_GpE.
DR   Pfam; PF03864; Phage_cap_E; 1.
PE   1: Evidence at protein level;
KW   Capsid protein; Direct protein sequencing; Host cytoplasm; Late protein;
KW   Reference proteome; Virion.
FT   CHAIN           1..351
FT                   /note="Major capsid protein"
FT                   /id="PRO_0000414623"
SQ   SEQUENCE   351 AA;  40277 MW;  A6296E4D8E438195 CRC64;
     MRPIPSLQNN FEYTDLTEPM ILIPNVWGLT QQLGIFGVDR TTQESVTLEE ITKSFGLMED
     IHRGARHQVG RDYDRQMRTF AVPHFTYDDY ITPRDIQGKR AYGKQELETL DQVRMRKLER
     LRGTHAATME FARMHTLVTG KPYTPNNTVG GATGYDWYQE FGKTRFEVNF ELDTPTTNIL
     EKSELVYAHM QDEAYTGGVV GDVIAICSPE FFSKLISHPT VVEAYKYYAS QPQILRERLR
     ARGFDARYRE FYFGNVLYIE YRGGFQGRPG GEKRRYVPAG EAVFIPGSGT EDLFKTFFAP
     ASKFEHVNTP GEESYAFEYV DPKGEFLEIN SETNFINVLM YPQLVVKGKA A