ID   CAPSD_BPLP2             Reviewed;         393 AA.
AC   D3WAC5;
DT   02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT   20-APR-2010, sequence version 1.
DT   23-FEB-2022, entry version 18.
DE   RecName: Full=Capsid protein {ECO:0000303|PubMed:24027307};
DE   AltName: Full=Gene product 6 {ECO:0000305};
DE            Short=gp6 {ECO:0000305};
OS   Lactococcus phage p2 (Lactococcus lactis bacteriophage p2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Skunavirus.
OX   NCBI_TaxID=254252;
OH   NCBI_TaxID=1358; Lactococcus lactis.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Tremblay D.M., Deveau H., Moineau S.;
RT   "Complete genomic sequence of Lactococcus lactis phage p2.";
RL   Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   SUBCELLULAR LOCATION, PROTEOLYTIC CLEAVAGE, AND ALTERNATIVE INITIATION.
RX   PubMed=22820334; DOI=10.1128/aem.01755-12;
RA   Labrie S.J., Tremblay D.M., Moisan M., Villion M., Magadan A.H.,
RA   Campanacci V., Cambillau C., Moineau S.;
RT   "Involvement of the major capsid protein and two early-expressed phage
RT   genes in the activity of the lactococcal abortive infection mechanism
RT   AbiT.";
RL   Appl. Environ. Microbiol. 78:6890-6899(2012).
RN   [3]
RP   STRUCTURE BY ELECTRON MICROSCOPY (13 ANGSTROMS) OF THE CAPSID, FUNCTION,
RP   SUBUNIT, AND SUBCELLULAR LOCATION.
RX   PubMed=24027307; DOI=10.1128/jvi.02033-13;
RA   Bebeacua C., Tremblay D., Farenc C., Chapot-Chartier M.P., Sadovskaya I.,
RA   van Heel M., Veesler D., Moineau S., Cambillau C.;
RT   "Structure, adsorption to host, and infection mechanism of virulent
RT   lactococcal phage p2.";
RL   J. Virol. 87:12302-12312(2013).
CC   -!- FUNCTION: Capsid protein self-assembles to form an icosahedral capsid
CC       with a T=7 symmetry, about 69 nm in diameter, and consisting of 60
CC       capsid proteins hexamers and 11 pentamers. The capsid encapsulates the
CC       genomic DNA. {ECO:0000269|PubMed:24027307}.
CC   -!- SUBUNIT: Homomultimer. {ECO:0000269|PubMed:24027307}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000269|PubMed:22820334,
CC       ECO:0000269|PubMed:24027307}. Note=Main component of the capsid.
CC       {ECO:0000269|PubMed:22820334, ECO:0000269|PubMed:24027307}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative initiation; Named isoforms=2;
CC       Name=Capsid protein large {ECO:0000269|PubMed:22820334};
CC         IsoId=D3WAC5-1; Sequence=Displayed;
CC       Name=Capsid protein short {ECO:0000269|PubMed:22820334};
CC         IsoId=D3WAC5-2; Sequence=VSP_058628;
CC   -!- PTM: Probably cleaved by the viral protease during maturation.
CC       {ECO:0000305|PubMed:22820334}.
CC   -!- SIMILARITY: Belongs to the Skunalikevirus capsid protein family.
CC       {ECO:0000305}.
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DR   EMBL; GQ979703; ADC80082.1; -; Genomic_DNA.
DR   Proteomes; UP000002348; Genome.
DR   GO; GO:0039620; C:T=7 icosahedral viral capsid; IDA:UniProtKB.
DR   InterPro; IPR024455; Phage_capsid.
DR   TIGRFAMs; TIGR01554; major_cap_HK97; 1.
PE   1: Evidence at protein level;
KW   Alternative initiation; Capsid protein; Coiled coil; Reference proteome;
KW   T=7 icosahedral capsid protein; Virion.
FT   CHAIN           1..393
FT                   /note="Capsid protein"
FT                   /id="PRO_0000438231"
FT   COILED          5..69
FT                   /evidence="ECO:0000255"
FT   VAR_SEQ         1..75
FT                   /note="Missing (in isoform Capsid protein short)"
FT                   /evidence="ECO:0000269|PubMed:22820334"
FT                   /id="VSP_058628"
SQ   SEQUENCE   393 AA;  43705 MW;  98237FC3B0B2EC22 CRC64;
     MNKPDLIEKQ NRLAELKENN VSLKSQISGF EVKNAIEDLP KVQELEKTLS ENSIEIIKIE
     NELNAQEEKP KGKDKMTNFI ESQNAVTEFF DVLKKNSGKS EIKNAWSAKL AENGVTITDT
     TFQLPRKLVE SINTALLNTN PVFKVFHVTN VGALLVSRSF DSANEAQVHK DGQTKTEQAA
     TLTIDTLEPV MVYKLQSLAE RVKRLQMSYS ELYNLIVAEL TQAIVNKIVD LALVEGDGTN
     GFKSIDKEAD VKKIKKITTK AKSAGKTPFA DAIEEAVDFV RPTAGRRYLI VKTEDRKALL
     DELRQATANA NVRIKNDDTE IASEVGVDEI IVYTGSKALK PTVLVDQKYH IDMQDLTKVD
     AFEWKTNSNM ILVETLTSGH VETYNAGAVI TVS