ID   Y1289_ARCFU             Reviewed;         346 AA.
AC   O28980;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Putative GTPase AF_1289;
DE            EC=3.6.-.-;
GN   OrderedLocusNames=AF_1289;
OS   Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS   100126 / VC-16).
OC   Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC   Archaeoglobus.
OX   NCBI_TaxID=224325;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX   PubMed=9389475; DOI=10.1038/37052;
RA   Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA   Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA   Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA   Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA   Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA   Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA   Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA   Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA   Smith H.O., Woese C.R., Venter J.C.;
RT   "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT   archaeon Archaeoglobus fulgidus.";
RL   Nature 390:364-370(1997).
CC   -!- FUNCTION: May have GTPase activity. May also bind and hydrolyze ATP.
CC       May function as chaperone (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB
CC       subfamily. {ECO:0000305}.
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DR   EMBL; AE000782; AAB89957.1; -; Genomic_DNA.
DR   PIR; H69410; H69410.
DR   RefSeq; WP_010878785.1; NC_000917.1.
DR   AlphaFoldDB; O28980; -.
DR   SMR; O28980; -.
DR   STRING; 224325.AF_1289; -.
DR   EnsemblBacteria; AAB89957; AAB89957; AF_1289.
DR   GeneID; 24794902; -.
DR   KEGG; afu:AF_1289; -.
DR   eggNOG; arCOG01226; Archaea.
DR   HOGENOM; CLU_043725_1_0_2; -.
DR   OMA; WMWERID; -.
DR   OrthoDB; 80898at2157; -.
DR   PhylomeDB; O28980; -.
DR   Proteomes; UP000002199; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR005129; GTPase_ArgK.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00750; lao; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; GTP-binding; Hydrolase; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..346
FT                   /note="Putative GTPase AF_1289"
FT                   /id="PRO_0000157822"
FT   BINDING         53..61
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         201
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         257..259
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   346 AA;  38527 MW;  ECA7CCA3A0267479 CRC64;
     MKPEEIVEGL LSGNRRALAR AITYVENEYP ESKEIMRQIF AKTGRAHVVG LTGFPGVGKS
     TLVSKLTEEF RRRGKKVGII AIDPGSPFTG GALLGDRLRL DGMDSRKQLW TDPGIFFRSM
     SSRGRAGGLA AKTGDVVRLL DAFGFDVILV ETVGAGQSEV DIIEVADTSV VVMMPETGDE
     IQVNKAGILE IGDIYVVNKA DLGGAEKVER WLRYMLSLDE ESVQMLSQMT HADEARVQSG
     EFFERRKGWN PPVIKTVADR GEGIKELADA IEEHFDYMKK TGLIEKRRRE RVKRELFEIV
     MNDVIKLVKE KTNYRDLLVK LLKGETDPYT AAEQIVEEVI HNAGKG