Y1301_ARATH
ID Y1301_ARATH Reviewed; 634 AA.
AC Q9SA69;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=BTB/POZ domain-containing protein At1g03010;
GN OrderedLocusNames=At1g03010; ORFNames=F10O3.17;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP DOMAIN BTB.
RX PubMed=15749712; DOI=10.1074/jbc.m413247200;
RA Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L.,
RA Vierstra R.D.;
RT "Cullins 3a and 3b assemble with members of the broad
RT complex/tramtrack/bric-a-brac (BTB) protein family to form essential
RT ubiquitin-protein ligases (E3s) in Arabidopsis.";
RL J. Biol. Chem. 280:18810-18821(2005).
CC -!- FUNCTION: May act as a substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex (CUL3-RBX1-BTB) which mediates the
CC ubiquitination and subsequent proteasomal degradation of target
CC proteins. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- DOMAIN: The BTB/POZ domain mediates the interaction with some component
CC of ubiquitin ligase complexes. {ECO:0000269|PubMed:15749712}.
CC -!- SIMILARITY: Belongs to the NPH3 family. {ECO:0000255|PROSITE-
CC ProRule:PRU00982}.
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DR EMBL; AC006550; AAD25808.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27514.1; -; Genomic_DNA.
DR PIR; G86160; G86160.
DR RefSeq; NP_171800.1; NM_100182.3.
DR AlphaFoldDB; Q9SA69; -.
DR iPTMnet; Q9SA69; -.
DR PaxDb; Q9SA69; -.
DR PRIDE; Q9SA69; -.
DR ProteomicsDB; 242531; -.
DR EnsemblPlants; AT1G03010.1; AT1G03010.1; AT1G03010.
DR GeneID; 839556; -.
DR Gramene; AT1G03010.1; AT1G03010.1; AT1G03010.
DR KEGG; ath:AT1G03010; -.
DR Araport; AT1G03010; -.
DR TAIR; locus:2007564; AT1G03010.
DR eggNOG; ENOG502QSDZ; Eukaryota.
DR HOGENOM; CLU_005994_6_0_1; -.
DR InParanoid; Q9SA69; -.
DR OrthoDB; 387335at2759; -.
DR PhylomeDB; Q9SA69; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9SA69; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SA69; baseline and differential.
DR Genevisible; Q9SA69; AT.
DR GO; GO:0009860; P:pollen tube growth; IEP:TAIR.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.30.710.10; -; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR043454; NPH3/RPT2-like.
DR InterPro; IPR027356; NPH3_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR32370; PTHR32370; 1.
DR Pfam; PF03000; NPH3; 1.
DR SUPFAM; SSF54695; SSF54695; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS51649; NPH3; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; Phosphoprotein; Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..634
FT /note="BTB/POZ domain-containing protein At1g03010"
FT /id="PRO_0000409569"
FT DOMAIN 38..103
FT /note="BTB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT DOMAIN 205..503
FT /note="NPH3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00982"
FT COILED 542..580
FT /evidence="ECO:0000255"
FT MOD_RES 444
FT /note="Phosphotyrosine"
FT /evidence="ECO:0000250|UniProtKB:Q9FMF5"
SQ SEQUENCE 634 AA; 71160 MW; D693829594DBBE68 CRC64;
MGLVTVGELK PAFTGKRGFR LNSTIRHASE WPISDVSSDL TVQVGSSSFC LHKFPLVSRS
GKIRKLLADP KISNVCLSNA PGGSEAFELA AKFCYGINIE INLLNIAKLR CASHYLEMTE
DFSEENLASK TEHFLKETIF PSILNSIIVL HHCETLIPVS EDLNLVNRLI IAVANNACKE
QLTSGLLKLD YSFSGTNIEP QTPLDWWGKS LAVLNLDFFQ RVISAVKSKG LIQDVISKIL
ISYTNKSLQG LIVRDPKLEK ERVLDSEGKK KQRLIVETIV RLLPTQGRRS SVPMAFLSSL
LKMVIATSSS ASTGSCRSDL ERRIGLQLDQ AILEDVLIPI NLNGTNNTMY DIDSILRIFS
IFLNLDEDDE EEEHHHLQFR DETEMIYDFD SPGSPKQSSI LKVSKLMDNY LAEIAMDPNL
TTSKFIALAE LLPDHARIIS DGLYRAVDIY LKVHPNIKDS ERYRLCKTID SQKLSQEACS
HAAQNERLPV QMAVQVLYFE QIRLRNAMSS SIGPTQFLFN SNCHQFPQRS GSGAGSGAIS
PRDNYASVRR ENRELKLEVA RMRMRLTDLE KDHISIKQEL VKSNPGTKLF KSFAKKISKL
NSLFSFSSLK PSLSGKASSE SRFLFQRKRR HSVS
