ID   CAPSD_BPP21             Reviewed;         342 AA.
AC   P68650; P36270;
DT   07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT   07-DEC-2004, sequence version 1.
DT   12-AUG-2020, entry version 44.
DE   RecName: Full=Major capsid protein {ECO:0000255|HAMAP-Rule:MF_04133};
DE   AltName: Full=Gene product 7 {ECO:0000305};
DE   AltName: Full=Gene product E {ECO:0000255|HAMAP-Rule:MF_04133};
DE            Short=gpE {ECO:0000255|HAMAP-Rule:MF_04133};
DE   AltName: Full=Major head protein {ECO:0000255|HAMAP-Rule:MF_04133};
GN   Name=E {ECO:0000255|HAMAP-Rule:MF_04133}; Synonyms=7;
OS   Enterobacteria phage P21 (Bacteriophage 21) (Bacteriophage P21).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae; Lambdavirus.
OX   NCBI_TaxID=10711;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8472949; DOI=10.1016/0378-1119(93)90583-o;
RA   Smith M.P., Feiss M.;
RT   "Sequence analysis of the phage 21 genes for prohead assembly and head
RT   completion.";
RL   Gene 126:1-7(1993).
CC   -!- FUNCTION: Assembles to form an icosahedral capsid with a T=7 symmetry.
CC       The icosahedral capsid is about 60 nm in diameter and composed of 415
CC       major capsid proteins. The assembly is primed by the interaction
CC       between capsid assembly protease and portal dodecamer, and major capsid
CC       proteins assemble cooperatively to form the procapsid with the help of
CC       capsid scaffolding protein. Major capsid protein forms hexons and
CC       pentons of the icosahedron. Viral genomic DNA is packaged into the
CC       procapsid through the portal vertex. The packaging triggers a dramatic
CC       reconfiguration of the capsid shell. {ECO:0000255|HAMAP-Rule:MF_04133}.
CC   -!- SUBUNIT: Homomultimer. {ECO:0000255|HAMAP-Rule:MF_04133}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04133}. Host
CC       cytoplasm {ECO:0000255|HAMAP-Rule:MF_04133}. Note=Forms the capsid
CC       icosahedric shell. {ECO:0000255|HAMAP-Rule:MF_04133}.
CC   -!- SIMILARITY: Belongs to the lambda phage major capsid protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04133}.
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DR   EMBL; M81255; AAA32346.1; -; Genomic_DNA.
DR   SMR; P68650; -.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0039620; C:T=7 icosahedral viral capsid; IEA:UniProtKB-KW.
DR   HAMAP; MF_04133; CAPSID_LAMBDA; 1.
DR   InterPro; IPR005564; Major_capsid_GpE.
DR   Pfam; PF03864; Phage_cap_E; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Host cytoplasm; Late protein;
KW   T=7 icosahedral capsid protein; Virion.
FT   CHAIN           1..342
FT                   /note="Major capsid protein"
FT                   /id="PRO_0000077566"
SQ   SEQUENCE   342 AA;  38569 MW;  4F1325DC11647A0D CRC64;
     MGLFTTRQLL GYTEQKVKFR ALFLELFFRR TVNFHTEEVM LDKITGKTPV AAYVSPVVEG
     KVLRHRGGET RVLRPGYVKP KHEFNYQQAV ERLPGEDPSQ LNDPAYRRLR IITDNLKQEE
     HAIVQVEEMQ AVNAVLYGKY TMEGDQFEKI EVDFGRSTKN NITQGSGKEW SKQDRDTFDP
     THDIDLYCDL ASGLVNIAIM DGTVWRLLNG FKLFREKLDT RRGSNSQLET AVKDLGAVVS
     FKGYYGDLAI VVAKTSYIAE DGIEKRYLPD GMLVLGNTAA DGIRCYGAIQ DAQALSEGVV
     ASSRYPKHWL TVGDPAREFT MTQSAPLMVL PDPDEFVVVQ VK