ID   Y1308_METAC             Reviewed;         230 AA.
AC   Q8TR74;
DT   02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=UPF0173 metal-dependent hydrolase MA_1308 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=MA_1308;
OS   Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS   C2A).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=188937;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
RX   PubMed=11932238; DOI=10.1101/gr.223902;
RA   Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA   Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA   Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA   McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA   Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R.,
RA   Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J.,
RA   Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A.,
RA   White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H.,
RA   Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V.,
RA   Zinder S.H., Lander E., Metcalf W.W., Birren B.;
RT   "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT   physiological diversity.";
RL   Genome Res. 12:532-542(2002).
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; AE010299; AAM04726.1; -; Genomic_DNA.
DR   RefSeq; WP_011021328.1; NC_003552.1.
DR   AlphaFoldDB; Q8TR74; -.
DR   SMR; Q8TR74; -.
DR   STRING; 188937.MA_1308; -.
DR   EnsemblBacteria; AAM04726; AAM04726; MA_1308.
DR   GeneID; 1473196; -.
DR   KEGG; mac:MA_1308; -.
DR   HOGENOM; CLU_070010_4_0_2; -.
DR   InParanoid; Q8TR74; -.
DR   OMA; WHGHSTW; -.
DR   OrthoDB; 76909at2157; -.
DR   PhylomeDB; Q8TR74; -.
DR   Proteomes; UP000002487; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..230
FT                   /note="UPF0173 metal-dependent hydrolase MA_1308"
FT                   /id="PRO_0000156395"
SQ   SEQUENCE   230 AA;  24790 MW;  73D50DA1EB7351E9 CRC64;
     MADLKITWLG HAAFLLEAEK KLLIDPFISE NPKAPCTPEE LNPDIIAVTH GHRDHLGDTI
     EIGARTGCRI ISIHEVANYI KSKGVFAEGM NKGGTVDLEG VTLTMTQALH SSSIDASGFS
     FDGGSPAGFV IGIGGHSIYH AGDTGIFGDM QLIGELYEPE IALLPIGSRF TMGIKEAVKA
     VELIEPQIVV PMHYNTFDVI KQDPEVFRKA VEAKVDTKVI ILDPGESIEL