ID   CAPSD_BPPH8             Reviewed;         341 AA.
AC   P05481;
DT   01-NOV-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1988, sequence version 1.
DT   02-DEC-2020, entry version 73.
DE   RecName: Full=Major capsid protein {ECO:0000255|HAMAP-Rule:MF_04133};
DE   AltName: Full=Gene product 5 {ECO:0000305};
DE   AltName: Full=Gene product E {ECO:0000305};
DE   AltName: Full=Major head protein {ECO:0000255|HAMAP-Rule:MF_04133};
GN   Name=E; Synonyms=5;
OS   Enterobacteria phage phi80 (Bacteriophage phi-80).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Siphoviridae.
OX   NCBI_TaxID=10713;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3267214; DOI=10.1093/nar/16.2.764;
RA   Kitao S., Nakano E.;
RT   "Nucleotide sequence from bacteriophage phi 80 with high homology to the
RT   major coat protein gene of lambda.";
RL   Nucleic Acids Res. 16:764-764(1988).
CC   -!- FUNCTION: Assembles to form an icosahedral capsid with a T=7 symmetry.
CC       The icosahedral capsid is about 60 nm in diameter and composed of 415
CC       major capsid proteins. The assembly is primed by the interaction
CC       between capsid assembly protease and portal dodecamer, and major capsid
CC       proteins assemble cooperatively to form the procapsid with the help of
CC       capsid scaffolding protein. Major capsid protein forms hexons and
CC       pentons of the icosahedron. Viral genomic DNA is packaged into the
CC       procapsid through the portal vertex. The packaging triggers a dramatic
CC       reconfiguration of the capsid shell. {ECO:0000250|UniProtKB:P03713}.
CC   -!- SUBUNIT: Homomultimer. {ECO:0000255|HAMAP-Rule:MF_04133}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04133}. Host
CC       cytoplasm {ECO:0000255|HAMAP-Rule:MF_04133}. Note=Forms the capsid
CC       icosahedric shell. {ECO:0000255|HAMAP-Rule:MF_04133}.
CC   -!- SIMILARITY: Belongs to the lambda phage major capsid protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04133}.
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DR   EMBL; X06751; CAA29926.1; -; Genomic_DNA.
DR   PIR; S03314; VHBP80.
DR   SMR; P05481; -.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04133; CAPSID_LAMBDA; 1.
DR   InterPro; IPR005564; Major_capsid_GpE.
DR   Pfam; PF03864; Phage_cap_E; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Coiled coil; Host cytoplasm; Late protein; Virion.
FT   CHAIN           1..341
FT                   /note="Major capsid protein"
FT                   /id="PRO_0000077564"
FT   COILED          109..129
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_04133"
SQ   SEQUENCE   341 AA;  38055 MW;  BCDAE15ED85785E2 CRC64;
     MSVYTTAQLL AVNEKKFKFD PLFLRIFFRE TYPFSTEKVY LSQIPGLVNM ALYVSPIVSG
     KVIRSRGGST SEFTPGYVKP KHEVNPLMMT LRLPDEDPQN VADPVYRRRR IILQNMKDEE
     LAIAQVEEKQ AVSAVLSGKY TMTGEAFEPV EVDMGRSAGN NIVQAGAAAW STRDKETYDP
     TDDIEAYALN ARGVVNIIVF DPKGWALFRS FKAVEKKLDT RRGSNSELET AVKDLGMAVS
     YKGMFGDVAI VVYSGQYVEN DVKKNYLPDL TMVLGNTQAR GLRTYGCILD ADAQREGIDA
     STRYPKNWVQ LGDPVREFTM IQSAPLMLLP DPDAFVSVKL A