ID   Y1312_METJA             Reviewed;         321 AA.
AC   Q58708;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=UPF0026 protein MJ1312;
GN   OrderedLocusNames=MJ1312;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000305};
CC       Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3
CC       cysteines and an exchangeable S-adenosyl-L-methionine. {ECO:0000305};
CC   -!- SIMILARITY: Belongs to the UPF0026 family. {ECO:0000305}.
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DR   EMBL; L77117; AAB99319.1; -; Genomic_DNA.
DR   PIR; G64463; G64463.
DR   RefSeq; WP_010870829.1; NC_000909.1.
DR   AlphaFoldDB; Q58708; -.
DR   SMR; Q58708; -.
DR   STRING; 243232.MJ_1312; -.
DR   DNASU; 1452214; -.
DR   EnsemblBacteria; AAB99319; AAB99319; MJ_1312.
DR   GeneID; 1452214; -.
DR   KEGG; mja:MJ_1312; -.
DR   eggNOG; arCOG00953; Archaea.
DR   HOGENOM; CLU_058377_0_0_2; -.
DR   InParanoid; Q58708; -.
DR   OMA; CIYCELG; -.
DR   OrthoDB; 73459at2157; -.
DR   PhylomeDB; Q58708; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006638; Elp3/MiaB/NifB.
DR   InterPro; IPR040084; GTPase_Obg.
DR   InterPro; IPR007197; rSAM.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01083; Uncharacterised_Radical_SAM_Su; 1.
DR   SMART; SM00729; Elp3; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   S-adenosyl-L-methionine.
FT   CHAIN           1..321
FT                   /note="UPF0026 protein MJ1312"
FT                   /id="PRO_0000217863"
FT   DOMAIN          11..236
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   BINDING         27
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
FT   BINDING         31
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
FT   BINDING         34
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   321 AA;  37131 MW;  0035C4E648DA607F CRC64;
     MTIAFGPVPS RRLGKSLGIN SIPCKFCSYD CVYCQVGRTI NKTIERREFY SPEDIFKSVE
     ERIGKLNNEK IDYLTFVADG EPTLDINLSK EVEMLRDFDI PIAIITNSSL IWREDVRNDI
     LNFDLVSFKV DSVDEKIWRE INRPHKDLVL DKILEGMIAF RDNYKGELIT ETMILGSIKY
     TEESIIKTAE FLKELNPNKC YLNTPIRPPS EKYIKPPKIE VITKILAIFN EIIGKNKIKL
     LGKFEGNEFI FSENVEEDIL AITSVHPMRE EVIKELLNKS NISFDIINKM VNEGKLIKLE
     YDGKVFYMKN IKSRDKNVSN P