ID   Y1315_STAAW             Reviewed;         279 AA.
AC   Q8NWR0;
DT   28-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=DegV domain-containing protein MW1315;
GN   OrderedLocusNames=MW1315;
OS   Staphylococcus aureus (strain MW2).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=196620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MW2;
RX   PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA   Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA   Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT   "Genome and virulence determinants of high virulence community-acquired
RT   MRSA.";
RL   Lancet 359:1819-1827(2002).
CC   -!- FUNCTION: May bind long-chain fatty acids, such as palmitate, and may
CC       play a role in lipid transport or fatty acid metabolism. {ECO:0000250}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000033; BAB95180.1; -; Genomic_DNA.
DR   RefSeq; WP_000166059.1; NC_003923.1.
DR   PDB; 4X9X; X-ray; 1.20 A; A=1-279.
DR   PDBsum; 4X9X; -.
DR   AlphaFoldDB; Q8NWR0; -.
DR   SMR; Q8NWR0; -.
DR   EnsemblBacteria; BAB95180; BAB95180; BAB95180.
DR   KEGG; sam:MW1315; -.
DR   HOGENOM; CLU_048251_3_2_9; -.
DR   OMA; EIHAKIN; -.
DR   Proteomes; UP000000418; Chromosome.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1180.10; -; 1.
DR   InterPro; IPR003797; DegV.
DR   InterPro; IPR043168; DegV_C.
DR   Pfam; PF02645; DegV; 1.
DR   TIGRFAMs; TIGR00762; DegV; 1.
DR   PROSITE; PS51482; DEGV; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Lipid-binding.
FT   CHAIN           1..279
FT                   /note="DegV domain-containing protein MW1315"
FT                   /id="PRO_0000209792"
FT   DOMAIN          4..278
FT                   /note="DegV"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00815"
FT   BINDING         61
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
FT   BINDING         93
FT                   /ligand="hexadecanoate"
FT                   /ligand_id="ChEBI:CHEBI:7896"
FT                   /evidence="ECO:0000250|UniProtKB:Q9X1H9"
FT   STRAND          5..9
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   HELIX           16..21
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          25..27
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          30..33
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          36..39
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   TURN            40..42
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   HELIX           46..54
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          59..62
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   HELIX           66..76
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   TURN            77..79
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          83..88
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   TURN            90..92
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   HELIX           95..103
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          105..108
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          110..114
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   HELIX           120..134
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   HELIX           139..150
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          153..158
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   HELIX           162..168
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          171..173
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          185..191
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          194..203
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   HELIX           204..219
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          224..233
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   HELIX           235..249
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          255..258
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   HELIX           261..267
FT                   /evidence="ECO:0007829|PDB:4X9X"
FT   STRAND          272..278
FT                   /evidence="ECO:0007829|PDB:4X9X"
SQ   SEQUENCE   279 AA;  30645 MW;  8EF8143A10F66D6F CRC64;
     MTKQIIVTDS TSDLSKEYLE ANNIHVIPLS LTIEGASYVD QVDITSEEFI NHIENDEDVK
     TSQPAIGEFI SAYEELGKDG SEIISIHLSS GLSGTYNTAY QASQMVDANV TVIDSKSISF
     GLGYQIQHLV ELVKEGVSTS EIVKKLNHLR ENIKLFVVIG QLNQLIKGGR ISKTKGLIGN
     LMKIKPIGTL DDGRLELVHN ARTQNSSIQY LKKEIAEFIG DHEIKSIGVA HANVIEYVDK
     LKKVFNEAFH VNNYDINVTT PVISAHTGQG AIGLVVLKK